DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6006 and slc22a15.1

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	XP_031751719.1	Gene:	slc22a15.1 / 448510	XenbaseID:	XB-GENE-959503	Length:	560	Species:	Xenopus tropicalis

Alignment Length:	507	Identity:	134/507 - (26%)
Similarity:	234/507 - (46%)	Gaps:	55/507 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 LMGHYGKWQL----LMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHMPVATWRNLSGS 148
            |:|..|.:|:    |:.|||.|:.......|:.                 |...|...|.|.|.:
Frog    35 LVGEMGIYQIYLSFLLAVLLQLYSATEAIIITI-----------------LGATPPYHWMNDSLT 82

  Fly   149 VDNCRRWEGIDWSQVSNETTLPSDWKTPAEMDKKLVACEKWEYETNDNVGN--TWTSQWDLVCEK 211
            .:..|   |..:..           :.|||.:...|..:          ||  :..|:|.||...
Frog    83 ANGSR---GKQYGS-----------QLPAEGEHGHVVFD----------GNFTSIVSEWFLVGGA 123

  Fly   212 EHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTLRALL 276
            .:..:|:...:..||..|.|..|.|||:||||.:......|:.:|.:...:...|.|:|..|.|:
Frog   124 AYEVSVSSSVYFGGVLIGVISFGQLSDRFGRKPVYVTGLALEVVFAVMNALTPIFPLFLLTRFLV 188

  Fly   277 GLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQLCIGIPGIF 341
            |:::..::....:|..|.:...:...||........:.....:.:.|..:.::.|.|.:.:.|..
Frog   189 GVMNGGMSLVAFVLLNECIGASYWAAAGSLGSLCFAVGIAQFALIGYFIRSWRLLALLVNVQGAA 253

  Fly   342 LCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTPPTQESS-TQDVTYLFRSS 405
            :..|...:|||||||..:||:.|.:..:.:..:.|.|:: ..:.|.|..::|: :.::..::.::
Frog   254 VLALSLCIPESPRWLHAQGRLREAQESLLSLGRRNRRKV-TSFTLCPRQKDSAHSANILTIYSNA 317

  Fly   406 YLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAVAMYIIT--KVGKKW 468
            .||:.::....:||..:|||||:.|:....||::|||.||:||.|:||..:.||:|.  :||::.
Frog   318 ILRQRTLIMMWVWFVCSLVYYGLTLSSGDLGGDIYLNLALSGLAELPAYPLCMYLINHKRVGRRG 382

  Fly   469 LFCATLICAGVACCCAAITEGHADLLWLKI----TFLMMGKFTISAGNTIMPVYTAELYPTPIRN 529
            .....|...|.||....:..|......|.:    |..::||..|||...|:.:|::|||||.:||
Frog   383 SLAGFLCVGGGACLLIMLVPGKTGSGPLSVLNSQTLSLLGKLNISAAFNIVYIYSSELYPTCVRN 447

  Fly   530 VGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGFVVLFLPET 581
            :|:|.|::.:.:..|:.|::..|......|...:..|..:..|.:.|.||||
Frog   448 LGMGVCSMFSRIGGIIAPFIPALRFAHWALPFIVFGAAGVSAGLLSLLLPET 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	131/503 (26%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	102/363 (28%)
slc22a15.1	XP_031751719.1	MFS	90..497	CDD:421695	113/428 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920