DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6006 and CG17752

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_650817.1	Gene:	CG17752 / 42337	FlyBaseID:	FBgn0038718	Length:	538	Species:	Drosophila melanogaster

Alignment Length:	532	Identity:	118/532 - (22%)
Similarity:	205/532 - (38%)	Gaps:	84/532 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 GHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHMPVATWRNLSGSVDNCRR 154
            |::|.:|:|:..|.....:.::.|..|....:......|..|.:
  Fly    11 GNFGPYQILLLGLYGYTNIVSSLHYFSQTLISFTPSHRCSAPVE--------------------- 54

  Fly   155 WEGIDWSQVSNETTLPS------DWKTPAEMDKKLVACEKWEYETNDNVGNTWTSQWDLVCEKEH 213
                ::||  |.|.|.|      |....:..|.|   |..|:::...|. .:.|::.:.||:..:
  Fly    55 ----EFSQ--NFTELLSCSVIQYDVDMTSFRDNK---CSSWDFDKESNY-ESITTELEWVCDDAY 109

  Fly   214 LKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTLRALLGL 278
            ...|.:.||.:|.|.|.|..|||:|:.||    ..:.||.|:.|      :|.:.:.:....|.:
  Fly   110 KLAVGQSFFFIGSALGSIFFGYLADRIGR----LPACVLSTLTG------ASGDFFTSFVGSLPM 164

  Fly   279 VSVSVTYSGL----------ILAIEYVDGKWRT-----IAGMYNLFPLPISYMIISGLAYLTQDY 328
            .|.:...|||          ||..||:..:.||     |.|::    ..|..||...:|....::
  Fly   165 FSFTRFISGLSMDTQYVLMYILVFEYLSPQHRTFGLNIILGVF----YSIGLMISPWIAIWLGNW 225

  Fly   329 QRLQLCIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADY--------- 384
            :.......:|.:.:......:.||..|||.||:.|:....:::.|||||||:....
  Fly   226 RSYLWAASLPALGMLIFPLFLHESVEWLLTKGKFDKAVNNLKSVAKFNGRQVEDSVFDEFIKHYR 290

  Fly   385 QLTPPTQESSTQDVTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLV 449
            :.....|:.|:.....:.|:..||:.:|........:.:.:..:..|:...|.:.:...:.:|.|
  Fly   291 EKLNSAQKKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFV 355

  Fly   450 EIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEGHAD------LLWLKITFLMMGKFTI 508
            .:|.....:....|:|:|.:.||:|:.............|..|      ||...:   .:.:|..
  Fly   356 VLPGGLSIILFQNKIGRKGMACASLLVGAFITATTGYLVGTLDPANYSVLLGFMV---CLARFGA 417

  Fly   509 SAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGF 573
            .........|.||:.||.:|..||...:|........:.|:..|......|...|::...|.|..
  Fly   418 VVAYDAEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLLISFLLIIGAC 482

  Fly   574 VVLFLPETAVRQ 585
            :.|.||||..:|
  Fly   483 LCLTLPETLHKQ 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	115/526 (22%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	87/386 (23%)
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	118/532 (22%)
CG17752	NP_650817.1	MFS	116..488	CDD:119392	88/388 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	5	5.060