Protein Alignment CG6006 and slc22a4

DIOPT Version :10

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_989323.1
• Gene: slc22a4 / 394948
• XenbaseID: XB-GENE-5858686
• Length: 553
• Species: Xenopus tropicalis
• Alignment Length: 542
• Identity: 162/542 - (29%)
• Similarity: 266/542 - (49%)
• Gaps: 74/542 - (13%)

  Fly    78 DEDETDVIGDLMGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRP--AQLQHMPVA 140
            |.||..   ..:|.:|::|.::..|||...:||.|:..|.::.|...:..|..|  |.|.    |
 Frog     3 DYDEAT---SFLGEWGRYQFMIFFLLSASIIPNGFNGMSVMFLAGIPEHRCHIPESANLS----A 60

  Fly   141 TWRNLS-----GSVDNCRRW----------------EGIDWSQVSNETTLPSDWKTPAEMDKKLV 184
            .|||.|     |....|||:                ..:|.:.:..|..|
 Frog    61 AWRNASIPRQDGQDSQCRRYRLGTLTNYSALGLLPGRDVDVTGIEQEPCL--------------- 110

  Fly   185 ACEKWEYETNDNVGNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFIS 249
              :.|.|..:..: :|..::||:|||.:....:....|.:||..|..:||.|||.||||.:||::
 Frog   111 --DGWNYSKSLYL-STIVTEWDIVCENDWKGPLTTSLFFVGVLLGSFVSGQLSDSFGRKKILFVT 172

  Fly   250 AVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYN--LFPLP 312
            ..:||.|.:.....:|:|::..|..::|:..:|...:..||..|.:....|.|.....  :| ..
 Frog   173 MAIQTGFSIVQVFSTSWEMFAILFLIVGMGQISNYVAAFILGTEILGKSARIIFSTLGTCIF-FA 236

  Fly   313 ISYMIISGLAYLTQDYQRLQLCIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNG 377
            |.||::...||..:|::.|.|.:.|||:|...||:::||||:||:.|||::|...||..|||.|
 Frog   237 IGYMMLPLFAYFIRDWRTLLLALTIPGLFCIPLWWIIPESPQWLICKGRLEEAEVIIRKAAKIN- 300

  Fly   378 RQLPADYQLTPPTQESSTQDVTYLFRSSY----------LRRISICFFCIWFTMNLVYYGIILNM 432
             ::||...:...|:   .:|:....:.||          :|.|:|....:|...::.|:||.||.
 Frog   301 -RVPAPAVIFKTTE---LEDIAERQKRSYTLLDLVKTFNVRIITIMTVFLWLITSIGYFGISLNT 361

  Fly   433 SSFGGNVYLNSALAGLVEIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEGHADLLWLK 497
            .:..|:.:||..|...:|:|:...|..::..:.:::..|.:|:..||......:..  .||..|.
 Frog   362 PNLHGDPFLNCFLLAAIEVPSNIFAWLLLRYISRRYSMCGSLLLGGVVLLLIQLVP--LDLQILS 424

  Fly   498 ITFLMMGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTP---YLSLLNKIEGHL 559
            ...:|:|||.::|..:::.|||||||||.|||.|||..:|::.:..:::|   ||...|::..::
 Frog   425 TVLVMVGKFGVTAAFSMVYVYTAELYPTVIRNTGVGIGSVSSRIGSVISPYFVYLGAYNRLLPYI 489

  Fly   560 LMTLLTAWSIFGGFVVLFLPET 581
            ||..||   :..|.:|||.|||
 Frog   490 LMGSLT---VANGILVLFFPET 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	MFS_SLC22	189..579	CDD:340875	129/404 (32%)
slc22a4	NP_989323.1	2A0119	12..516	CDD:273328	159/530 (30%)