DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6006 and Slc22a13

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_001119757.1	Gene:	Slc22a13 / 316062	RGDID:	1306840	Length:	551	Species:	Rattus norvegicus

Alignment Length:	515	Identity:	155/515 - (30%)
Similarity:	263/515 - (51%)	Gaps:	45/515 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 MGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQ---------RPAQLQHMPVATWRN 144
            :|.:|::|:.:|:|:.:....:.|.:.|.::...::..:|.         ..:..:.:.|:...:
  Rat    11 VGDFGRFQVRLTILMGIPNFLSAFFVFSQVFMVLDEAHYCSVSWVKNHTFNLSAAEQLAVSIPND 75

  Fly   145 LSGSVDNCRRW---------EGIDWSQVSNETTLPSDWKTPAEMDKKLVACEK-WEYETNDNVGN 199
            .:|..::|..:         |.| .|...|||.                ||:. |:|.  :|...
  Rat    76 TAGRPESCLMFRPPPDNASLEDI-LSHRFNETQ----------------ACDSGWDYP--ENRPP 121

  Fly   200 TWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICS 264
            :..:::|||||:|:||..::..|:.|:..|.::.|.:.|..||:..|.:..:|..|..:.....|
  Rat   122 SLKNEFDLVCERENLKRTSQSVFMAGLLVGALVFGPVCDWIGRRPSLLMQLLLSGIASMATAFVS 186

  Fly   265 SFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQ 329
            |||||:|||..|...:.....|..:|..|:|....||.|.:.......:..|.::||||..::::
  Rat   187 SFELYMTLRFALATANAGFLLSSNVLLSEWVGTSRRTRAMVLAQSNFALGLMALAGLAYGVRNWR 251

  Fly   330 RLQLCIGIPGIF-LCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADY--QLTPPTQ 391
            .||: ||...|| |.|.::|:||||||||.:||.:|.:::::.||..|||.|.::.  ||. |.:
  Rat   252 LLQI-IGTTPIFLLVFYFWVLPESPRWLLSQGRTEEAKQLVQKAALVNGRPLASELLNQLV-PEK 314

  Fly   392 ESSTQDVTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAV 456
            ...:.:...|||...||::::....:||..:|:|||:...:..||.::||...:.|:||:||...
  Rat   315 TGPSGNALDLFRHPQLRKVTLILIAVWFVDSLLYYGLGFQVGDFGLDIYLTQVIFGVVEVPARLS 379

  Fly   457 AMYIITKVGKKWLFCATLICAGVACCCAAITEGHADLLWLKITFLMMGKFTISAGNTIMPVYTAE 521
            ::.::.|:|:||....||..|||.|.......|  ||..:.....::|||..||..||..|||||
  Rat   380 SIPMMEKLGRKWSQLCTLTLAGVMCVIIIFIPG--DLPTVATALAVVGKFASSAAFTISYVYTAE 442

  Fly   522 LYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGFVVLFLPET 581
            |.||.||..|:|..::.:.:..|:||.:.||.:....:.|.:..:..|..|.:...||||
  Rat   443 LLPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHKAIPMLIFGSLPIGAGLLCALLPET 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	153/512 (30%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	121/359 (34%)
Slc22a13	NP_001119757.1	2A0119	12..510	CDD:273328	155/514 (30%)
Slc22a13	NP_001119757.1	MFS	139..500	CDD:119392	121/364 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020