DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6006 and Slc22a15

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_001101177.1	Gene:	Slc22a15 / 310732	RGDID:	1311184	Length:	548	Species:	Rattus norvegicus

Alignment Length:	524	Identity:	146/524 - (27%)
Similarity:	234/524 - (44%)	Gaps:	80/524 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 MGHYGKWQL----LMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHMPVATW------R 143
            :|..|.:|:    |:.|||.|:.......|                 |.:...|...|      .
  Rat    10 VGEMGLYQMYLCFLLAVLLQLYVATEAILI-----------------ALIGATPAYHWDMAELLP 57

  Fly   144 NLSGSVDNCRRWEGIDWSQVSNETTLPSDWKTPAEMDKKLVACEKWEYETNDNVGNTWT---SQW 205
            |.|.|            :|.|.:.....||         |:.....|...:.:..|::|   |:|
  Rat    58 NQSHS------------NQSSGKGQAFGDW---------LLTANGSEIHKHVHFSNSFTSIASEW 101

  Fly   206 DLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYL 270
            .|:..:.:..:.|..||..||..|.|..|.|||:||||.:......|..:|.:......|:|.:.
  Rat   102 FLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSYEFFA 166

  Fly   271 TLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYN--LFPLPISYMIISGLAYLTQDYQRLQL 333
            ..|.|:|:::..::....:|..|.|...:..:||...  .|.:.|:...:  |.|..:.::.|.:
  Rat   167 VTRFLVGMMNGGMSLVAFVLLNECVGAAYWALAGSIGGLFFAVGIAQYAL--LGYFIRSWRTLAI 229

  Fly   334 CIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTPPTQESSTQDV 398
            .:.:.|..:..|...:|||||||..:||:.|....:...||.| |:|...:.||.|...|..:..
  Rat   230 LVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRN-RKLKCTFSLTHPANRSYRETG 293

  Fly   399 TY--LFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAVAMYII 461
            ::  |||...|...::....|||..:|||||:.|:....||::|.|.||:||:|||:..:.:|:|
  Rat   294 SFLDLFRYRVLLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLI 358

  Fly   462 TK--VGKKWLFCATLICAGVACCCA------------AITEGHADLLWLKITFLMMGKFTISAGN 512
            .:  .|:|....|.|...|:||...            |:...|        :..::||.||||..
  Rat   359 NQRWFGRKRTLAAFLCLGGLACLIVMFLPEKKDTGVFAVVNSH--------SLSLLGKLTISAAF 415

  Fly   513 TIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGFVVLF 577
            .|:.:||:|||||.|||||:|.|::.:.:..|:.|::..|..::..|...:..|..:..|.:.|.
  Rat   416 NIVYIYTSELYPTVIRNVGLGTCSMFSRVGGIIAPFVPSLKDVQWSLPFIVFGATGLTSGLLSLL 480

  Fly   578 LPET 581
            ||||
  Rat   481 LPET 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	144/521 (28%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	114/374 (30%)
Slc22a15	NP_001101177.1	MFS	111..469	CDD:119392	113/368 (31%)
Slc22a15	NP_001101177.1	MFS_1	111..450	CDD:284993	110/349 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920