Protein Alignment CG6006 and Slc22a22

DIOPT Version :10

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_001013969.1
• Gene: Slc22a22 / 299944
• RGDID: 1304605
• Length: 555
• Species: Rattus norvegicus
• Alignment Length: 542
• Identity: 138/542 - (25%)
• Similarity: 236/542 - (43%)
• Gaps: 68/542 - (12%)

  Fly    89 MGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWC-------QRPAQLQHMPVATWRNLS 146
            :|..|::|:.|.|:|::..:.::.|.....:.||.....|       .|......|.:.|...:.
  Rat    10 VGDRGRFQIWMIVVLNILSMVSSLHDVIENFTAAIPAHHCSVNLLDTSRSEISMAMNLTTEAMMK 74

  Fly   147 GSV--------DNCRR-----WEGIDWS-QVSNETTLPSDWKTPAEMDKKLVAC-EKWEYETNDN 196
            .|:        :.|||     |:.||.: ..||.|.|.::            .| :.|.|: :..
  Rat    75 VSIPMGPNQKPEQCRRFRHPQWQFIDSNISTSNSTELETE------------PCLDGWTYD-HSV 126

  Fly   197 VGNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLY 261
            ..:|..::|||||:.:..|..|:...|.|........|.:||:||||.:|...::...|.|....
  Rat   127 FTSTIVTEWDLVCDFQSFKYYAQATSLAGHFVAAPFCGIISDRFGRKPLLMYCSLAYGILGTCCA 191

  Fly   262 ICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWR-TIAGMYNLFPLPISYMIISGLAYLT 325
            ...:|.||..||.|....:.:|..:.|||.:|....:|. |:..:..||. ......:.||||:.
  Rat   192 FVPNFSLYCVLRFLSSASASTVGMNCLILVLEETSVQWHATVIVLSGLFS-STGLAGLGGLAYVL 255

  Fly   326 QDYQRLQLCIGIPG--IFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTP 388
            .|:..:||...:|.  .|:.|.|  ||||.|||::.|:.|:..:.::..|..||::..|....|.
  Rat   256 SDWHLIQLTSALPYFIFFILFCW--VPESARWLMITGKTDQALKELQRIASINGKKDIAQNLTTE 318

  Fly   389 PTQESSTQDVTYLFR---------SSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSA 444
            ..:....:||....:         :..:|:|.:|:..:.|......:|::|::...|.|:::...
  Rat   319 DLRSKVKEDVCSTVKHFSIKDIIINPMIRKIVLCYSSVLFAELFSIFGLLLDVHMLGKNIFVTQI 383

  Fly   445 LAGLVEIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEG-HADLLWLKITFLMMGKFTI 508
            |.|:::||:.::..:|:..|.::.|....|...|   .|..||.. ..|:..|::...::||...
  Rat   384 LLGVIDIPSKSLTYFILRNVRRRPLIAFLLFATG---GCITITMFLSEDMYVLRLAIFILGKGCF 445

  Fly   509 SAGNTIMPVYTAELYPTPIRNVGVG-------ACNVAAGLALILTPYLSLLNKIEGHLLMTLLTA 566
            :|..:|...|..||.|.|:|:...|       ..:|.:.|.|:...|..||..|...:|..:.|
  Rat   446 AAFISINTAYCNELSPVPLRSTLNGIYISVARLASVLSALTLVTRKYFVLLPMIFCGVLPIVAT- 509

  Fly   567 WSIFGGFVVLFLPETAVRQKTD 588
                  ..:.|||||.....||
  Rat   510 ------INIYFLPETFNHPITD 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	MFS_SLC22	189..579	CDD:340875	107/409 (26%)
Slc22a22	NP_001013969.1	MFS_OAT	109..516	CDD:340932	110/432 (25%)