DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6006 and Slc22a20

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_001381833.1	Gene:	Slc22a20 / 293686	RGDID:	1311460	Length:	556	Species:	Rattus norvegicus

Alignment Length:	521	Identity:	148/521 - (28%)
Similarity:	250/521 - (47%)	Gaps:	35/521 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 TDVIGDLMGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHMPV---ATW- 142
            ||:: |.:|..|::||:.|.||.|.......|.....:.||.....||.||.......   ..|
  Rat     4 TDLL-DALGGVGRFQLVYTALLLLPCGLLACHTFLQNFTAAAPPHHCQHPANYTEATTNDSGAWL 67

  Fly   143 -----RNLSGSVDNCRRWEGIDWSQVSNETTLPSDWKTPAEMDKKLVACEKWEYETNDNVGNTWT 202
                 .|..|..:.|:|:....|:.:...|   |......|..|     :.|.|: .....:|..
  Rat    68 RATIPLNQHGVPEPCQRYTEPQWALLEPNT---SSHGVATEGCK-----DGWVYD-RSIFPSTIV 123

  Fly   203 SQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFE 267
            .:||||||...|:::|:..::.||..|..:.|.|:|:.|||..|..|.:...:.|.......||.
  Rat   124 MEWDLVCEARTLRDLAQSIYMSGVLVGAALFGSLADRLGRKAPLVWSYLQLAVSGAVTAYVGSFS 188

  Fly   268 LYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQ 332
            .|...|.|:|:....:..:.|.|.:|::..:.||:||:...|...:..:|::|:|||.:.::.||
  Rat   189 AYCIFRFLMGMTFSGIILNSLSLVVEWMPTRGRTVAGILLGFSFTLGQLILAGVAYLIRPWRWLQ 253

  Fly   333 LCIGIPG-IFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTPPTQESSTQ 396
            ..:..|. :|..:.|: :|||.||||:.|:..:..:.:...|..|||:...: :||.....|..|
  Rat   254 FAVSAPFLVFFLYSWW-LPESSRWLLLHGKAQQAVQNLRKVAMMNGRKAEGE-RLTIEVVSSYIQ 316

  Fly   397 D----------VTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEI 451
            :          :..|||:..:|:::.|...:||:.::.|||:.:::..||.::||..||.|:::|
  Rat   317 NEFASVRTSNSILDLFRTPGIRKVTCCLMMVWFSNSVAYYGLAMDLQKFGLSIYLVQALFGIIDI 381

  Fly   452 PAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEGHADLLWLKITFLMMGKFTISAGNTIMP 516
            ||:.||...:..||::....:.|:.||:.........  .||..|:.....:||..:::....:.
  Rat   382 PAMLVATTTMIYVGRRATVSSFLVLAGLMVIANMFVP--EDLQTLRTVQAALGKGCLASSFICVY 444

  Fly   517 VYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGF-VVLFLPE 580
            ::|.|||||.||.:|:|..:|.|.|..:..|.::.|.:|...|......|.|:..|. |:.||.|
  Rat   445 LFTGELYPTEIRQMGMGFASVNARLGGLAAPLITTLGEISPVLPPVSFGATSVLAGMAVICFLTE 509

  Fly   581 T 581
            |
  Rat   510 T 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	143/511 (28%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	106/368 (29%)
Slc22a20	NP_001381833.1	MFS_SLC22A6_OAT1_like	103..508	CDD:341004	119/414 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010