DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6006 and Slc22a26

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	XP_017173677.1	Gene:	Slc22a26 / 236149	MGIID:	2385316	Length:	553	Species:	Mus musculus

Alignment Length:	577	Identity:	144/577 - (24%)
Similarity:	243/577 - (42%)	Gaps:	105/577 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 DLMGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHMPVATW--------- 142
            :|:|.:|::|:|....|.:..|....|:....:.|||....|             |
Mouse     8 NLVGSHGRFQILQMAFLLICNVITMPHVILENFTAANLGHRC-------------WVHIIDNDTN 59

  Fly   143 -RNLSGSV------------------DNCRRWEGIDW---------SQVSNETTLPSDWKTPAEM 179
             .|.||.:                  :.|||:....|         |.::...|.|
Mouse    60 SNNNSGILSQDDLLRISIPLDSNLRPEKCRRFVQPQWHLLQFNGSFSNMTEPDTEP--------- 115

  Fly   180 DKKLVACEKWEYETNDNVGNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKT 244
                 ..:.|.|:....:..|.| :|:|||..:.|.:||:..||:||..|..:.|:||||||||
Mouse   116 -----CMDGWVYDQRTFLSTTVT-EWNLVCGSQELNSVAKFIFLIGVLAGHFVGGHLSDKFGRK- 173

  Fly   245 MLFISAVLQ-TIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNL 308
            :||..|:|| .|.|....:..:|.:|..||.|.||..:.:..:.::|.:|:...|.:.:....::
Mouse   174 LLFRCALLQMAITGTCTALAPTFFIYCLLRFLTGLCIIPINTNSVLLMLEWTSPKTQALVTTLSM 238

  Fly   309 FPLPISYMIISGLAYLTQDYQRLQLCIGIPGIFLCFL----WFVVPESPRWLLVKGRIDEVRRII 369
            .......:|::|||:..|::..|||.|.:| ||:..:    |  :.||.|||:|..:..:..:.:
Mouse   239 SSHHFGGLILAGLAFAFQNWHHLQLAISVP-IFVLLIPTSRW--LTESARWLIVTNKPQKALQEL 300

  Fly   370 EAAAKFNG-------------RQLPADYQLTPPTQESSTQDVTYLFRSSYLRRISICFFCIW-FT 420
            ...|..||             |.:..| ::..|..:.|.:|   ||....||: .:|..|:. |.
Mouse   301 RKVASKNGIKNSEDVLTMEVVRTIMKD-EIAIPRTKPSLRD---LFHMPNLRK-RLCLLCLLRFL 360

  Fly   421 MNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAA 485
            ......||.:|:....|||:|..:|.....|||.|:..:::..:|::  ....|.|........:
Mouse   361 QISPTVGINMNLQHLKGNVFLTQSLTSAFSIPATALGGFLLNYIGRR--ISQLLPCLLFGIFLLS 423

  Fly   486 ITEGHADLLWLKITFLMMGKFTISAGNTIM-----PVYTAELYPTPIRNVGVGACNVAAGLALIL 545
            |.....::..|.:..:     |::.|::.|     .:|::||.||.||...:|...:..|:...|
Mouse   424 IVSVPQEMQTLLVVLI-----TLAGGSSAMIYNSNVLYSSELMPTVIRATALGVIGICGGVGAAL 483

  Fly   546 TPYLSLLNKIEGHLLMTLLTAWSIFGGFVVLFLPETAVRQKTDNQGGSSANASAAKQ 602
            :|.:.:|......|...:....||.||.:.|.||||..:...|:.........::||
Mouse   484 SPLIMILTLYSASLPWIIYGVLSILGGLLPLILPETKNQPLPDSIQDVECGWESSKQ 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	138/551 (25%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	103/380 (27%)
Slc22a26	XP_017173677.1	MFS	109..506	CDD:391944	111/427 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010