Protein Alignment CG6006 and Slc22a3

DIOPT Version :9

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_035525.1
• Gene: Slc22a3 / 20519
• MGIID: 1333817
• Length: 551
• Species: Mus musculus
• Alignment Length: 563
• Identity: 150/563 - (26%)
• Similarity: 259/563 - (46%)
• Gaps: 82/563 - (14%)

  Fly    90 GHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKD-FWCQRPAQLQHMPVATWRNLSGSVDNCR 153
            |.:|::|..:.:||.|..|...|.....::..:..| :||:.|            ..:...:.|.
Mouse    12 GEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGSQPDYYWCRGP------------RATALAERCA 64

  Fly   154 RWEGIDWSQVSNETTLPSDWK--------------TPAEM-----------DKKLVACE-KWEY- 191
            .....:|:..:.|..:|::.:              |.:|:           ...||:|. .|.|
Mouse    65 WSPEEEWNLTTPELHVPAERRGQGHCHRYLLEATNTSSELSCDPLTAFPNRSAPLVSCSGDWRYV 129

  Fly   192 ETNDNVGNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIF 256
            ||:    :|..||:||||....:.::.:....||...|....||.:|::||..:..||.....|.
Mouse   130 ETH----STIVSQFDLVCSNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLIIYLISCFGVGIT 190

  Fly   257 GLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGL 321
            |:.:....:|.:::..|.|.|:.......:..::..|.|..|.|.|.|:.......:..:|:.|:
Mouse   191 GVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGI 255

  Fly   322 AYLTQDYQRLQLCIGIPG-IFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADY- 384
            ||.|..:|.:||.|.:|. :||.:.| |||||||||:.:.:.::..:|:...||.||:.|.::|
Mouse   256 AYFTPSWQGIQLAISLPSFLFLLYYW-VVPESPRWLITRKQGEKALQILRRVAKCNGKHLSSNYS 319

  Fly   385 QLTPPTQESSTQDVTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLV 449
            ::|...:|.|......|.|:..:|:.::.....|||..:||.|:::.:...|||:|::..::|||
Mouse   320 EITVTDEEVSNPSCLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGLIGGNLYIDFFISGLV 384

  Fly   450 EIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAA-ITEGHADLLWLKITFLMMGKFTISAGNT 513
            |:|...:.:..|.::|::..|.|:.|.|||:|...| :.||   :.||:.|...:|:..|:....
Mouse   385 ELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFLPEG---IPWLRTTVATLGRLGITMAFE 446

  Fly   514 IMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAW----------- 567
            |:.:..:|||||.:||.||..|:.......|:.|:          ||..|...|
Mouse   447 IVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPF----------LLFRLAAIWLELPLIIFGIL 501

  Fly   568 -SIFGGFVVLF-------LPETAVRQKTDNQGGSSANASAAKQ 602
             |:.||.|:|.       ||||.  :..:..|.|..:....|:
Mouse   502 ASVCGGLVMLLPETKGIALPETV--EDVEKLGSSQLHQCGRKK 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	145/540 (27%)
		MFS	222..579	CDD:119392	111/378 (29%)
Slc22a3	NP_035525.1	2A0119	12..523	CDD:273328	145/540 (27%)
		MFS	145..513	CDD:119392	111/381 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020