Protein Alignment CG6006 and Slc22a2

DIOPT Version :10

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_038695.1
• Gene: Slc22a2 / 20518
• MGIID: 1335072
• Length: 553
• Species: Mus musculus
• Alignment Length: 538
• Identity: 149/538 - (27%)
• Similarity: 262/538 - (48%)
• Gaps: 65/538 - (12%)

  Fly    85 IGDLMGHYGKWQL-------LMTVLLSLFQ-----------VPNTFHISSSIYQAANKDFWCQRP 131
            :.|::.|.|::.|       |:.:|...|.           .||....|..:.:.:.:..|  .|
Mouse     4 VDDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPNHHCRSPGVAELSQRCGW--SP 66

  Fly   132 AQLQHMPVATWRNLSGSV---DNCRRWEGIDWSQ------------VSNETTLPSDWKTPAEMDK 181
            |:..:..|....: :|.|   ..|.|:| :||:|            .:|.:.||
Mouse    67 AEELNYTVPGLGS-AGEVSFLSQCMRYE-VDWNQSTLDCVDPLSSLAANRSHLP----------- 118

  Fly   182 KLVACEK-WEYETNDNVGNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTM 245
             |..||. |.|:|   .|::..::::|||....:.::.:....:|...|.:..|||:|:||||..
Mouse   119 -LSPCEHGWVYDT---PGSSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFC 179

  Fly   246 LFISAVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFP 310
            |.::.::..|.|:.:.|..::...|..|.|.||||.:....|.||..|:|...:|...|:.....
Mouse   180 LLVTILINAISGVLMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRTVGICYQIA 244

  Fly   311 LPISYMIISGLAYLTQDYQRLQLCIGIPGI-FLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAK 374
            ..:..:|::|:||...:::.||..:.:|.. ||.:.| .:|||||||:.:.:..:..:||:..||
Mouse   245 FTVGLLILAGVAYALPNWRWLQFAVTLPNFCFLLYFW-CIPESPRWLISQNKNAKAMKIIKHIAK 308

  Fly   375 FNGRQLPADYQ-LTPPTQESSTQDVTY--LFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFG 436
            .||:.:|...| ||.........:.::  |.|:..:|:.::.....|||.:::|.|:|::|...|
Mouse   309 KNGKSVPVSLQSLTADEDTGMKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMGLAG 373

  Fly   437 GNVYLNSALAGLVEIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEGHADLLWLKITFL 501
            .|:||:...:.|||.||..:.:..|.::|:::.:..:.:.||.||..:.....  ||.|||||..
Mouse   374 DNIYLDFFYSALVEFPAAFIIILTIDRIGRRYPWAVSNMVAGAACLASVFIPD--DLQWLKITVA 436

  Fly   502 MMGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTA 566
            .:|:..|:....::.:..||||||.|||:.|..|:....:..|:||:  |:.::....|...|..
Mouse   437 CLGRMGITIAYEMVCLVNAELYPTYIRNLAVLVCSSMCDIGGIVTPF--LVYRLTDIWLEFPLVV 499

  Fly   567 WSIFG---GFVVLFLPET 581
            :::.|   |.:||.||||
Mouse   500 FAVVGLVAGGLVLLLPET 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	MFS_SLC22	189..579	CDD:340875	117/396 (30%)
Slc22a2	NP_038695.1	2A0119	12..525	CDD:273328	147/530 (28%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O15244	284..288		3/3 (100%)