Protein Alignment CG6006 and Slc22a1

DIOPT Version :9

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_033228.2
• Gene: Slc22a1 / 20517
• MGIID: 108111
• Length: 556
• Species: Mus musculus
• Alignment Length: 571
• Identity: 156/571 - (27%)
• Similarity: 264/571 - (46%)
• Gaps: 81/571 - (14%)

  Fly    79 EDETDVIGDLMGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHMPVATWR 143
            :|..:.:|: .|.:.|...|:..|:|....|....|   ::.....|..|:.|...:......|.
Mouse     5 DDVLEHVGE-FGWFQKQAFLLLCLISASLAPIYVGI---VFLGFTPDHHCRSPGVAELSQRCGWS 65

  Fly   144 NLS---------GS------VDNCRRWEGIDWSQ------------VSNETTLPSDWKTPAEMDK 181
            ...         ||      :..|.::| :||:|            .:|.:.||
Mouse    66 PAEELNYTVPGLGSAGEASFLSQCMKYE-VDWNQSTLDCVDPLSSLAANRSHLP----------- 118

  Fly   182 KLVACEK-WEYETNDNVGNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTM 245
             |..||. |.|:|   .|::..::::|||......::.:....||...|.::.||::|:||||..
Mouse   119 -LSPCEHGWVYDT---PGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLC 179

  Fly   246 LFISAVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYV-DGKWRTIAGMYNLF 309
            |.::.::.::.|:...:...:...|..|.|.|:||.....||..|..|:| .|..||.|.:|.:
Mouse   180 LLVTTLVTSLSGVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQV- 243

  Fly   310 PLPISYMIISGLAYLTQDYQRLQLCIGIPG-IFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAA 373
            ...:..:.::|:||...|::.|||.:.:|. :||.:.|| |||||||||.:.|..:..||:|..|
Mouse   244 AFTVGLVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWF-VPESPRWLLSQKRTTQAVRIMEQIA 307

  Fly   374 KFNGRQLPADYQ---LTPPTQESSTQDVTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSF 435
            :.|.:..|||.:   |.....|..:.....|||:..||:.::....:||:..::|.|:|:::.:.
Mouse   308 QKNRKVPPADLKMMCLEEDASERRSPSFADLFRTPSLRKHTLILMYLWFSCAVLYQGLIMHVGAT 372

  Fly   436 GGNVYLNSALAGLVEIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEGHADLLWLKITF 500
            |.|:||:...:.|||.||..:.:..|.::|:.:...|:.:.|| |.|...|...| :|.||.:|.
Mouse   373 GANLYLDFFYSSLVEFPAAFIILVTIDRIGRIYPIAASNLVAG-AACLLMIFIPH-ELHWLNVTL 435

  Fly   501 LMMGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLT 565
            ..:|:...:....::.:..||||||.|||:|:..|:....|..|.||:          ::..|:.
Mouse   436 ACLGRMGATIVLQMVCLVNAELYPTFIRNLGMMVCSALCDLGGIFTPF----------MVFRLME 490

  Fly   566 AWS-----IFG------GFVVLFLPET---AVRQKTDNQGGSSANASAAKQ 602
            .|.     :||      |.|.|.||||   |:.:..:.........|.||:
Mouse   491 VWQALPLILFGVLGLSAGAVTLLLPETKGVALPETIEEAENLGRRKSKAKE 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	148/534 (28%)
		MFS	222..579	CDD:119392	115/372 (31%)
Slc22a1	NP_033228.2	2A0119	12..525	CDD:273328	152/546 (28%)
		MFS	125..515	CDD:119392	122/406 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020