Protein Alignment CG6006 and Slc22a25

DIOPT Version :10

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_620263.1
• Gene: Slc22a25 / 192273
• RGDID: 621104
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 563
• Identity: 139/563 - (24%)
• Similarity: 247/563 - (43%)
• Gaps: 92/563 - (16%)

  Fly    89 MGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAA--NKDFWCQRPAQLQHMPVATWRNLSGSVDN 151
            :|..|::|:|....:.:|.:..:.|.....:.|.  |...|         :|:.....:||: ||
  Rat    10 VGSLGRFQILQMTFILIFNIIISPHSLLENFTAVIPNHRCW---------VPILDNDTVSGN-DN 64

  Fly   152 -----------------------CRRWEGIDWSQVSNETTLPSDWKTPAEMDKKLVAC-EKWEYE 192
                                   |||:....|..:....|..|..:...|      .| :.|.|:
  Rat    65 GNLSQDDLLRVSIPLDSDLRPEKCRRFVQPQWDLLHLNGTFSSVTEPDTE------PCVDGWVYD 123

  Fly   193 TNDNVGNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFG 257
            .:..: :|..::||||||.:.|.::|:..||.|:..|.|:.|.|:|:|||:.:|..:::...:..
  Rat   124 QSTFL-STIITEWDLVCESQSLDSIAKFLFLTGILVGNILYGPLTDRFGRRLILICASLQMAVTE 187

  Fly   258 LWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLA 322
            .......:|.:|.:||.|.|:...:|..:..:|.||:...|::.:|....|....|...:::|||
  Rat   188 TCAAFAPTFLIYCSLRFLAGISFSTVLTNSALLIIEWTRPKFQALATGLLLCAGAIGQTVLAGLA 252

  Fly   323 YLTQDYQRLQLCIGIPGIFLCFLWFVVP-----ESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPA 382
            :..:::..|.|.:.:|..||     :||     ||.|||::..::.:..:.:...|..||.:...
  Rat   253 FTVRNWHHLHLAMSVPIFFL-----LVPTRWLSESARWLIMTNKLQKGLKELIKVAHINGMKNST 312

  Fly   383 DY------------QLTPPTQESSTQDVTYLFRSSYLRR----ISICFFCIWFTMNLVYYGIILN 431
            |.            :|.....:||..|   |||:..||:    :|:..|.:|.::    .|:::|
  Rat   313 DVLTIEVVRTIMKEELEASQTKSSLWD---LFRTPNLRKRICLLSLVRFVVWLSV----IGLLIN 370

  Fly   432 MSSFGGNVYLNSALAGLVEIPAIAVAMYIITKVGKK--WLFCATLICAGVACCCAAITEGHADLL 494
            ......||:|...|.|::.|||..|.::::..:|::  .||..:|.  |::............:|
  Rat   371 FQHLRINVFLLQCLLGIITIPANLVGIFLVNHLGRRISQLFIISLF--GISILAIIFVPQEMQIL 433

  Fly   495 WLKI-TFLMMGKFT-ISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEG 557
            .:.: ||  .|.|: :|..:.:  |:..||.||.||...:|...:|......|:|...:|.....
  Rat   434 RMVLATF--GGVFSFVSVSSAL--VHANELLPTIIRATALGVIGIAGSTGAALSPLFMILRTYSD 494

  Fly   558 HLLMTLLTAWSIFGGFVVLFLPETAVR------QKTDNQGGSS 594
            .|...:....|..||.|||.||||..:      |..:|:|.:|
  Rat   495 SLPWIIYGVLSFLGGLVVLLLPETKNQPLPDSIQDVENEGRAS 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	MFS_SLC22	189..579	CDD:340875	109/414 (26%)
Slc22a25	NP_620263.1	MFS_OAT	109..506	CDD:340932	105/421 (25%)