DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6006 and Y66D12A.13

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_499489.1	Gene:	Y66D12A.13 / 190497	WormBaseID:	WBGene00013439	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	473	Identity:	114/473 - (24%)
Similarity:	208/473 - (43%)	Gaps:	107/473 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 DWKTPA-EMDKKLVACEKWEYETNDNVGNTWTSQWDLVCEKEHLKNVAEMF------------FL 223
            |.:.|| |.:.|.||.|..|..:..|             |..::.::.::|            .:
Worm    71 DCEEPAMEYEFKSVAVEFQELCSRHN-------------EHSYMDSITQLFGVNNRVRFSTTSQM 122

  Fly   224 LGVATGGIISGYLSDKFGRK--TMLFISAVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYS 286
            :|:..|..|:|.|||.:|||  |:||:..:|  .|.......||.|:::.:|..:|:....:|..
Worm   123 IGIMLGSAIAGQLSDLYGRKKITLLFLCMML--FFSTSSSFSSSIEVFIIVRFFIGICCGGLTTV 185

  Fly   287 GLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRL-QLCIGIPGIFLCFLWFVVP 350
            |.||.:|.:....|  ..|..:.....:||:.:..||:|.:::.| ::|..:..|.:....|::|
Worm   186 GSILVVENLPSAHR--LWMSTVVTWAPNYMLFALFAYITGEWRCLARMCNAMTVIAILICAFLLP 248

  Fly   351 ESPRWLLV--KGRIDEVRRIIEAAAKFNGRQLPADYQLTPPTQESSTQDVT-------------- 399
            |||::|:.  ||:: .|:.|     |:..:......|||    ::..:||.
Worm   249 ESPKYLIQARKGKL-AVKSI-----KYINKFKRVRNQLT----DTEIEDVVHSAIEVDTKSRAKA 303

  Fly   400 --YLFRSSYLR----------RISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIP 452
              |.|...|:.          .||:      |:::.|.||::.|.....|::|:|:|::|.:...
Worm   304 KKYSFIHLYIHPKITVQTVVASISM------FSVSYVTYGLLFNYDVLTGSIYMNAAVSGFLRYV 362

  Fly   453 AIAVAMYII----TKVGKKWLFCATLICAGVACCCAAITEGH-ADLL-----WLK-ITFLMMGKF 506
            ..||...:.    ..||:|.:...|:  :.:.||...|...: .||:     |:: :|.|..|
Worm   363 VGAVVAVLDHFGGEHVGRKRMHFITV--SFIMCCMFGIFFIYFNDLVLEYKSWIRALTLLAFG-- 423

  Fly   507 TISAGNTIMP--VYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKI----EGHLLMTLLT 565
              :.|...:.  :.|||::||.|||:.....||...|..:..| :....|:    .|:|::.::.
Worm   424 --TTGCLFLQLLLITAEMFPTGIRNIASAHINVCGRLGNVFGP-MVFSYKLGFAGSGYLILGVIC 485

  Fly   566 AWSIFGGFVV--LFLPET 581
            ...:    :|  :|:|||
Worm   486 LLDV----IVFHIFIPET 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	112/471 (24%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	99/406 (24%)
Y66D12A.13	NP_499489.1	2A0119	36..506	CDD:273328	114/473 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010