DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6006 and Y51A2D.18

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_507620.2	Gene:	Y51A2D.18 / 180202	WormBaseID:	WBGene00013083	Length:	550	Species:	Caenorhabditis elegans

Alignment Length:	565	Identity:	136/565 - (24%)
Similarity:	230/565 - (40%)	Gaps:	122/565 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 VSGLDPADDEDETDVIGDLMGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQ----AANKDFWCQR 130
            |.|||        |.|     ..||:.||:.:...|..:|   .:||..|.    ||.:...|..
Worm    32 VHGLD--------DYI-----QMGKYVLLVCLAAELLILP---QVSSMFYMMYAGAAPRVISCDN 80

  Fly   131 PAQLQHMPVATWRNLSGSVDNCRRWEGIDWSQVSNETTLPSDWKTPAEMDKKLVACEKWEYETND 195
                     ..:.:|....:.|                        .|:| |:..|...|::...
Worm    81 ---------IVFDSLLEGKEIC------------------------FELD-KMGNCSHPEFQYQF 111

  Fly   196 NVGNTWTSQWDLVCEKEHL-KN--VAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFG 257
            ...|.   :::..|....| ||  ..:||   ||.||.|:.|.:||.||||....: |.|..:.|
Worm   112 RSINV---EYNYFCNTSKLVKNSISVQMF---GVLTGSIVFGQISDSFGRKIGSQV-ASLGMLIG 169

  Fly   258 LWLYICSSFE-LYLTL-RALLGLV---SVSVTYSGLILAIEYVDGK---WRTIAGMYNLFP-LPI 313
             ||.:..|.. |:.|: |.::|..   |:|:..   :..:|.:..|   |..:|..::  | :||
Worm   170 -WLIVVQSRNLLHFTISRTIVGFFTGGSISIIN---VFIMENIPKKHRMWINMAITWS--PNMPI 228

  Fly   314 -SYMIISGLAYLTQDYQRLQ-----LCIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAA 372
             ||     .|:|..|::.|.     :|  ||||.  |..|.:.||||||:.:|:|.|..::::..
Worm   229 YSY-----FAWLASDWKSLAYINAFMC--IPGIL--FFQFFIHESPRWLVTRGKISEAVQVLQRQ 284

  Fly   373 AKFNGRQ----------LPADYQLTPPTQESSTQDVTY-LFRSSYLRRISICFFCIWFTMNLVYY 426
            .|.:.::          |..:|..|.......|:...| ||.:..|...:|.....:...:::.|
Worm   285 LKTSNQENLIHEDFEENLRMEYAKTQAQNTRKTKFSYYHLFVTPKLAITTIVLAYSYCATSIINY 349

  Fly   427 GIILNMSSFGGNVYLNSALAGLVEIP---AIAVAMYIITKVGKKWLFCATLICAGVACCCA---- 484
            |::.||....|::|.||...||:...   :...|......:|:|::..:.|:...::....
Worm   350 GVLFNMEKLSGSIYWNSVYTGLMRYACNLSFGYADLKFKSIGRKFIHTSGLVIIVLSLSLVVGSY 414

  Fly   485 AITEGHADLLWLKITFLMMGKFT----ISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALIL 545
            |:...|.....::|:.|:....|    |:.|     :.:|||:|||||.:|.....:...:.::|
Worm   415 ALHLNHEMKDVIRISILLASSMTSQIYIADG-----IVSAELFPTPIRTIGYAFLQLWNRVGVVL 474

  Fly   546 TPYLSLLNKIEGHLLMTLLTAWSIFGGF-VVLFLPETAVRQKTDN 589
            :|::..|......|....:..:|:...| ....||||..|...::
Worm   475 SPFIFYLADYWLALPFCFMILFSLIDTFSFECLLPETKGRHLVEH 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	127/535 (24%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	99/394 (25%)
Y51A2D.18	NP_507620.2	2A0119	24..519	CDD:273328	136/563 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010