DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6006 and ZK892.3

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_496162.1	Gene:	ZK892.3 / 174558	WormBaseID:	WBGene00014127	Length:	541	Species:	Caenorhabditis elegans

Alignment Length:	510	Identity:	112/510 - (21%)
Similarity:	195/510 - (38%)	Gaps:	106/510 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 GKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHMP--VATWRNLSGSVDNCRRW 155
            |:|: |..:::.|:|:        :::.:|...|    ...|::||  ..|.:|.      |.:.
Worm     6 GQWR-LDVMMMCLYQM--------ALFFSAQLVF----VIFLEYMPKTACTEKNY------CYKL 51

  Fly   156 EG---IDWSQ-VSNETTLPSDWKTPAE---MDKKLVACEKWE-YETNDNVGNTWTSQWDLVCEKE 212
            |.   .|:.: ..|...:|:..|:..:   .|||.:..|..: |...|....|
Worm    52 ESKCLSDYDENKPNICLVPNGSKSQFDECVNDKKYLYFESAQHYYQQDCTSLT------------ 104

  Fly   213 HLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTLRALLG 277
            |......|:  |||....:|.|.|:||.||:.:.|.|..:..:..:......|...:...|...|
Worm   105 HYSASTNMY--LGVLFANLILGVLADKLGRRPIFFASIAIGVVSLILSAAIPSLIAFYIFRFTTG 167

  Fly   278 LVSVSVTYSGLILAIEYVDGK----WRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQ-LCIGI 337
            :........|.....|.:..|    .||.:...|      :.:::..:|::|:.:.... :|..|
Worm   168 VGVAGAQIVGWSYGSEMISAKRRFQLRTFSNWAN------ARILVVFVAFITRRWDTASYVCAAI 226

  Fly   338 PGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTPPTQESSTQDVTY-- 400
            ..:....|| .:||||.:|..|.||:|.....|..|:.    ...:|:.......::.:.:|:
Worm   227 SALIFPILW-KLPESPVFLEQKHRIEEANEAREQLAEL----CDMEYEEKEAAAINNLKKITFMD 286

  Fly   401 LFRSSYLRR--ISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAVAMYIITK 463
            |:|:..||.  :.:||  :||.:.:..|...||.:....|:|:...|:||         :..|:|
Worm   287 LWRNERLRTNFLVLCF--MWFFVGMATYITDLNGADMSTNLYVGQFLSGL---------LLTISK 340

  Fly   464 V------------GKKWLFCATLICAGVACCC-----AAITEGHADLLWLKITFLMMGKFTISAG 511
            :            |::.:|   |...|||...     .|:...:.:..|..|.:|....|...|.
Worm   341 IIFGFAEPRFEWLGRRAIF---LFSQGVAIIAYILILVALVTSNKETTWYLIVYLCAYSFQALAT 402

  Fly   512 NTIMPVYTAELYPTPIRNVGVGACNVAAGLALILT-----------PYLSLLNKI 555
            .|.. :..|||.||.:|.......|:...|..|:.           |.|.|:|.|
Worm   403 ETCY-LSVAELIPTDVRVTVAAITNICLRLGTIVASLTKPLKFSFEPGLFLINLI 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	112/510 (22%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	85/371 (23%)
ZK892.3	NP_496162.1	2A0119	<108..477	CDD:273328	86/377 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910