DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6006 and UST4r

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_599206.2	Gene:	UST4r / 171397	RGDID:	620976	Length:	552	Species:	Rattus norvegicus

Alignment Length:	536	Identity:	130/536 - (24%)
Similarity:	229/536 - (42%)	Gaps:	70/536 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 MGHYGKWQLLMTVLL---SLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHMPVA--TWRNLSGS 148
            :|..|::|:|..|.:   |:..||   ||....:.||.....|..|. |.::.|:  ..|.|:..
  Rat    10 VGGLGRFQILQMVFVVFTSVIVVP---HIIIENFTAAIPSHRCWVPI-LDNVTVSDNDSRILNQD 70

  Fly   149 --------------VDNCRRWEGIDWSQVSNETTLPSDWKTPAEMDKKLVAC-EKWEYETNDNVG 198
                          :|.|||:....|..:....|..|..:...|      .| :.|.|: ..|..
  Rat    71 KLLKISIPLDSHLRLDKCRRFAQPQWHLLDLNDTFSSITEPDTE------PCVDGWVYD-RSNFH 128

  Fly   199 NTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFIS----AVLQTIFGLW 259
            :|..::|:||||.:.|.:|.::.|::|...|||::|.|||:||||.:|..:    |:.:|
  Rat   129 STTVTEWNLVCESQALNSVTKLSFMIGAFIGGIVNGLLSDRFGRKFILKYALLQMAITET----- 188

  Fly   260 LYICSSFE----LYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISG 320
               |:.|.    :|.:||.|.|:....:|.:..:|..|:...|:.|:..:..........||::|
  Rat   189 ---CAGFAPNLFIYCSLRFLAGMSLEPITVNINLLMFEWTSPKFLTMVTVLGSCAGSFGGMILAG 250

  Fly   321 LAYLTQDYQRLQLCIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPAD-- 383
            ||:..|::..|||.:.:|..|...|...:.||.|||:|..:..:..:.::..|..||.:...|
  Rat   251 LAFQFQNWHHLQLAMSVPIFFFLILTRWLSESARWLIVINKPQKGLKELKKVAHINGMKKSGDNI 315

  Fly   384 ----------YQLTPPTQESSTQDVTYLFRSSYLRR--ISICFFCIWFTMNLVYYGIILNMSSFG 436
                      .:|.......|.:|   ||.:..||:  ..:.|..:.|.::.|  |:.:::....
  Rat   316 TMEVVRTSMKKELEAAKMRPSPRD---LFHTPILRKQIYILSFIRLLFILSGV--GVAIHLQHLS 375

  Fly   437 GNVYLNSALAGLVEIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEGHADLLWLKITFL 501
            .|:.|...|..:..|....:..:::..:|::......:...|::...|.......:.|...:..:
  Rat   376 NNIELLQILISVSSILFSVIGHFVLNHIGRRITQMVIMFLRGISILTAIFAPQEMETLRFIMAMM 440

  Fly   502 MMGKFTIS-AGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLT 565
            ..|...:| |.|::   :..||.||.:|....|...:...:...|.|...:|.....:|......
  Rat   441 AEGLAALSYAANSL---HANELLPTTLRATARGVIGMFGNIGFFLAPLCMMLASYSPNLPWIFYG 502

  Fly   566 AWSIFGGFVVLFLPET 581
            .::|..||:||.||||
  Rat   503 GFAILSGFIVLLLPET 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	128/533 (24%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	88/379 (23%)
UST4r	NP_599206.2	MFS_OAT	109..516	CDD:340932	101/429 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010