Protein Alignment CG6006 and Slc22a7

DIOPT Version :10

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_659105.2
• Gene: Slc22a7 / 108114
• MGIID: 1859559
• Length: 540
• Species: Mus musculus
• Alignment Length: 534
• Identity: 163/534 - (30%)
• Similarity: 263/534 - (49%)
• Gaps: 63/534 - (11%)

  Fly    89 MGHYGKWQLLMTVLLSL--FQVPNTFHISSSIYQAANKDFWC---QRPAQLQHMPVATW------ 142
            :|.:|.:||...|||:|  |.:|  .|....|:.||.....|   ..||.|.|..:  |
Mouse    10 VGGFGPFQLRNLVLLALPRFLLP--MHFLLPIFMAAVPAHHCALPDAPANLSHQDL--WLKTHLP 70

  Fly   143 RNLSGSVDNCRRWEGIDWSQVSNETTLPSDWKTPAEMDKK--LVACEK-WEYETNDNVGNTWTSQ 204
            |...||..:|.|:.   :.|.....||.::.....|.:.:  .|.|.: |||:.:: ..:|..::
Mouse    71 RETDGSFSSCLRFA---YPQALPNVTLGTEVYNSGEPEGEPLTVPCSQGWEYDRSE-FSSTIATE 131

  Fly   205 WDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELY 269
            |||||::..|..|....|.:||..|.::.|||||:|||:.:|.::.|.....||......::.::
Mouse   132 WDLVCQQRGLNKVTSTCFFIGVLLGAVVYGYLSDRFGRRRLLLVAYVSTLALGLMSAASVNYIMF 196

  Fly   270 LTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQL- 333
            :|.|.|.|......|...|.|.:|::|.:.||:||:.:........::::.:.||.:.::.|.|
Mouse   197 VTTRMLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTTFWTGGVLLLTLVGYLIRSWRWLLLA 261

  Fly   334 ----CIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTPP----- 389
                |  :|||.  .:|: ||||.||||.:||::|.::.:...||.|||.:..| .|:..
Mouse   262 ATLPC--VPGII--SIWW-VPESARWLLTQGRVEEAKKYLSICAKLNGRPISED-SLSQEALNKV 320

  Fly   390 -TQESSTQDVTY--LFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEI 451
             |.|..:|..:|  |||:|.||.:|:|...:||.:|..|||:.|:.|..|..||....|.|.||:
Mouse   321 ITMERVSQRPSYLDLFRTSQLRHVSLCCMMMWFGVNFSYYGLTLDASGLGLTVYQTQLLFGAVEV 385

  Fly   452 PAIAVAMYIITKVGKK----WLFCATLICAGVACCCAAITEGHADLLWLKITFLMMGKFTISAGN 512
            |:.....:::..||::    .:..||.:..|::...::.|:.     |: ...:::||....|..
Mouse   386 PSKITVFFLVRLVGRRLTEAGMLLATALTFGISLLVSSDTKS-----WI-TALVVIGKAFSEAAF 444

  Fly   513 TIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGF---- 573
            |...::|:|||||.:|..|:|...:...|...|.|.:.||:.:  .||:..|.    :||.
Mouse   445 TTAYLFTSELYPTVLRQTGMGFTALIGRLGASLAPLVVLLDGV--WLLLPKLA----YGGISFLA 503

  Fly   574 --VVLFLPETAVRQ 585
              .||.||||...|
Mouse   504 ACTVLLLPETKKAQ 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	MFS_SLC22	189..579	CDD:340875	127/412 (31%)
Slc22a7	NP_659105.2	2A0119	11..521	CDD:273328	163/533 (31%)