Protein Alignment CG6006 and slc22a23

DIOPT Version :10

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: XP_002936473.1
• Gene: slc22a23 / 100491610
• XenbaseID: XB-GENE-966989
• Length: 643
• Species: Xenopus tropicalis
• Alignment Length: 599
• Identity: 155/599 - (25%)
• Similarity: 242/599 - (40%)
• Gaps: 111/599 - (18%)

  Fly    60 AATPQSPAAAVSGLDPAD-----------DEDETDVIGDLMGHYGKWQLLMTVLLSLFQVPNTFH 113
            |.|.::|||.||...|..           |......:|.| |.|.|..:|:|.:.:||.   :|.
 Frog    30 APTEETPAAPVSPGRPEHCSRYNSLLLDYDGSVLPFLGGL-GSYNKRLVLLTWIPALFL---SFS 90

  Fly   114 ISSSIYQAANKDFWCQRPAQLQHMPVATWRNLSGSVDNCRRWEGIDWSQVSNET----------- 167
            ..|..:.....|.|||             .|.||.    ....|...|.|.|::
 Frog    91 QFSDFFLLDQPDKWCQ-------------VNSSGG----EHGPGRVVSHVGNDSSGGLLLLPPPQ 138

  Fly   168 --TLPSDWKTPAEMDKKLVACEKWEYETNDNVGNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGG 230
              |.|:........|..|  |.||:|.....:.....|:|||||:.....::|:...|:|:..|.
 Frog   139 LPTTPTPTSATNYTDSCL--CTKWDYRIRAGLVQNVVSKWDLVCDSSWKVHIAKFSLLVGMIFGY 201

  Fly   231 IISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYV 295
            :|:|.::|..||:.:|.||.:...||||.:.:.....::.|||...|.....:..|...|.||..
 Frog   202 LITGCVADWIGRRLVLLISVIFNLIFGLTVALSVDVNMFSTLRFFEGFCLAGIILSLYALRIELC 266

  Fly   296 DGKWR-------TIAGMYNLFPLPISYMIISGLAYLTQDYQRLQLCIGIPGIFLCFLWFVVPESP 353
            ....|       :..||...|.||       |:|.|.:|:|.||..|..|.|.:.|.|.:.|||.
 Frog   267 PPGHRFMITMVASFIGMAGQFLLP-------GIAALCRDWQVLQAVIICPFILMLFYWVIFPESL 324

  Fly   354 RWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTPPTQESSTQDVTYLFRSSYLRRISICFFCIW 418
            |||:...:.|..::.|......|...:.:|.:...|..|          |..|.|...:|...:.
 Frog   325 RWLMATMQFDASKKQILKMIHRNRVNMESDVKGVMPELE----------REVYTRPKKVCIVKVV 379

  Fly   419 FTMN------------LVYYGI-----------ILNMSSFGGNVYLN-SALAGLVEIPAIAVAMY 459
            .|.|            |..|||           .|| :||..|.|:| .|:||:.....:|:...
 Frog   380 GTRNLWKNILVLCVNSLTGYGIHHCFAKSLMDPELN-TSFMHNFYVNYFAMAGITLASCLAMCPV 443

  Fly   460 I--ITKVGKKWLF-----CATLICAGVACCCAAITE----GHADLLWLK--ITFLMMGKFTISAG 511
            :  :.:.|...||     .|:|:..|:.......::    |.:|::..|  |.|.::|.|:..|.
 Frog   444 VGFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQRPETGLSDIVKNKFSIIFSIIGMFSSHAV 508

  Fly   512 NTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTA-WSIFGGFVV 575
            .::...:.||:.||.||..|:|....:||...:..|.:.|.|: :|:.|..::.| .::.....:
 Frog   509 GSLSVFFCAEITPTVIRGGGLGLVLASAGFGSLTAPIMELHNQ-KGYFLHHIIFACCTLICIICI 572

  Fly   576 LFLPETAVRQKTDN 589
            |.|||:..:...:|
 Frog   573 LLLPESKNQNLPEN 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	MFS_SLC22	189..579	CDD:340875	114/434 (26%)
slc22a23	XP_002936473.1	MFS_SLC22A23	149..562	CDD:341002	116/433 (27%)