DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6006 and slc22a13

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	XP_031760340.1	Gene:	slc22a13 / 100491580	XenbaseID:	XB-GENE-959647	Length:	547	Species:	Xenopus tropicalis

Alignment Length:	524	Identity:	154/524 - (29%)
Similarity:	266/524 - (50%)	Gaps:	48/524 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 MGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQ-------RP--AQLQHMPVATWRN 144
            :|.:|::|..:.|:|||....|.||:.|.::........|.       .|  .:.:.:.....|:
Frog    11 VGEFGRFQKQLVVVLSLLSFLNAFHMFSQVFMEIPVPHRCDSRWILLINPNLTEAERLNYTIPRD 75

  Fly   145 LSGSVDNCRRWEGIDWSQVSNE-----TTLPSDWKTPAEMDKKLVACEK-WEYETNDNVGNTWTS 203
            ..|..:.|..:..:.|...|.|     :|.|               |:. |||:|::. .:|..:
Frog    76 GRGQYEQCLMYSPVQWDMESIEKFGLNSTGP---------------CQDGWEYDTSEQ-KSTLVT 124

  Fly   204 QWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFEL 268
            |:||||.:.....:::..::.|:..|.::.|.|.|:.||:.::.:|.:||.:|||.......|.:
Frog   125 QFDLVCHRREQTGISQSVYMSGLLIGALLFGPLGDRIGRRPVILLSMLLQLVFGLSAAFAPHFYV 189

  Fly   269 YLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQL 333
            |...|.::|.....:..:.|:|..|:|....|..|.:.......:..|.::|::|..::::.||:
Frog   190 YTAFRWVVGTSMSGLMINNLVLGAEWVGSSRRACATITAHVCFAVGLMALAGVSYGIRNWRLLQI 254

  Fly   334 CIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPAD--YQLTPPTQESSTQ 396
            ....|...|.|..:|:|||.||||.||:.::..::::.||..|.:::|.|  :|.   .:|.|.:
Frog   255 VSSAPTALLFFYIWVLPESARWLLTKGKKEKAVKLLKKAAAMNKKEIPEDLLFQF---NEEKSPK 316

  Fly   397 --DVTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAVAMY 459
              ::..|||:..||::::....:||..:|||||:.||:.|||.::||...:.|.|||||...||:
Frog   317 SGNMIDLFRNKTLRKLTLVMCLVWFVNSLVYYGLSLNVGSFGLDIYLTQLVFGAVEIPARIGAMF 381

  Fly   460 IITKVGKK--WLFCATLICAGVAC-CCAAITEGHADLLWLKITFL-MMGKFTISAGNTIMPVYTA 520
            .:...|:|  .:||  |...|..| ...||...    |.:.||.| ::|||:|::..:|..:|.|
Frog   382 AVQLFGRKPSQMFC--LFLGGTVCLIITAIPRN----LPIAITILAVIGKFSIASSFSICYIYAA 440

  Fly   521 ELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGFVVLFLPETAVRQ 585
            |::||.||..|||..::||.:|.|..|.:|||:|....:.|.:..:..|.||.:...||||..:.
Frog   441 EVFPTVIRQNGVGLASMAARVAGITAPLISLLDKYHAAIPMAIYGSGPIIGGILCFLLPETRNKD 505

  Fly   586 KTDN 589
            ..|:
Frog   506 LQDH 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	151/513 (29%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	117/364 (32%)
slc22a13	XP_031760340.1	2A0119	12..509	CDD:273328	153/521 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920