Protein Alignment CG6006 and slc22a6

DIOPT Version :10

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: XP_002937540.1
• Gene: slc22a6 / 100487511
• XenbaseID: XB-GENE-5842250
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 519
• Identity: 145/519 - (27%)
• Similarity: 241/519 - (46%)
• Gaps: 44/519 - (8%)

  Fly    89 MGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHMP-VATW-RNL-----S 146
            :|..|::|::..|||||.......|.....:.||.....||.....:... ...| |.|     :
 Frog    10 IGGMGRYQVIHVVLLSLPVFMLASHNLMQNFTAAIPRHRCQINGSFEETNFTGPWLRALVPMKPT 74

  Fly   147 GSVDNCRRWEGIDWSQVSNETTLPSDWKTPAEMDKKLVACEKWEYETNDNVGNTWTSQWDLVCEK 211
            |....|.|:....:..:.:..|...|     |::.: ...:.|.|: :....:|..:||||||..
 Frog    75 GEFSKCLRYTTPQYHLLMDNFTQNVD-----ELETE-TCVDGWVYD-HSEFASTIITQWDLVCNH 132

  Fly   212 EHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFE----LYLTL 272
            ..::.||:..::.||..|.::.|.|||||||:.:...|.:..::.|    ||::|.    .|...
 Frog   133 RRMRQVAQSIYMAGVLVGSVVFGGLSDKFGRRPLNIWSNLQMSVTG----ICAAFSPNYIWYCIF 193

  Fly   273 RALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQLCIGI 337
            |.|.|.....:..:...|.:|::....|........:...:..:::.|||::.:|:..|||...:
 Frog   194 RFLTGTALSGIVLNSYSLIVEWIPTGNRAFTSTATGYCYTMGQLVLVGLAFMIRDWHWLQLAASL 258

  Fly   338 PGIFLCFL--WFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQ----------LPADYQLTPPT 390
            | .|..||  |: :|||.|||::.|:.:...:.::..||.||::          |.:..|.....
 Frog   259 P-FFFYFLYSWW-IPESGRWLVLSGKPEVACKALKKVAKINGKKEAGEKLTVEVLKSSMQREISA 321

  Fly   391 QESSTQDVTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIA 455
            .:.||..|..|.|:..:||||.|..|.||:.:..|||:.|::.|||.::|:...:.|.|:|||..
 Frog   322 SKHSTYSVLDLVRTPVVRRISFCISCTWFSTSFAYYGLALDLQSFGVSIYIIQIIFGTVDIPAKF 386

  Fly   456 VAMYIITKVGKKWLFCATLICAGVAC---CCAAITEGHADLLWLKITFLMMGKFTISAGNTIMPV 517
            .:.:::|.:|::.|...|||.||:|.   .|..     .|...::.:..:.||..::|....:.:
 Frog   387 FSYFVMTYIGRRVLQALTLILAGIAILVNICVP-----QDYQTVRTSMAVFGKGCLAASFNCLFL 446

  Fly   518 YTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGFVVLFLPET 581
            ||.|||||.||..|:|...:.|.|..|:.|...:...|...|.:.:.....|..|....|||||
 Frog   447 YTGELYPTVIRQSGMGLGTMMARLGGIIAPLAQMTGDIYHSLPLIIFGCLPILSGIAGCFLPET 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	MFS_SLC22	189..579	CDD:340875	119/408 (29%)
slc22a6	XP_002937540.1	MFS_SLC22A6_OAT1_like	102..508	CDD:341004	119/418 (28%)