Protein Alignment CG6006 and sv2a

DIOPT Version :10

• Sequence 1: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: XP_012825002.1
• Gene: sv2a / 100379721
• XenbaseID: XB-GENE-968429
• Length: 729
• Species: Xenopus tropicalis
• Alignment Length: 552
• Identity: 99/552 - (17%)
• Similarity: 180/552 - (32%)
• Gaps: 190/552 - (34%)

  Fly   208 VCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTL 272
            :|..:..|.:..:...||:..|..:.|.::|:.||:..|.||..:.::|..:......:..:|..
 Frog   184 MCLSDSNKGMLGLIVYLGMMVGAFLWGGMADRIGRRQCLLISLSVNSVFAFFSSFVQGYGTFLFC 248

  Fly   273 RALLGL-----VSVSVTYSGLILA-------IEYVDGKWRTIAGMYNLFPLPISYMII------- 318
            |.|.|:     :.:..:|....||       :.::...| .|.|:|   ...:::.||
 Frog   249 RLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFW-MIGGIY---ASAMAWAIIPHYGWSF 309

  Fly   319 -SGLAYLTQDYQRLQLCIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPA 382
             .|.||....::...|....|.:|.......:|||||:.|..|:.||...:::.....|.|....
 Frog   310 QMGSAYQFHSWRVFVLVCAFPSVFAIGALTTMPESPRFFLENGKHDEAWMVLKQVHDTNMRAKGH 374

  Fly   383 DYQLTPPTQ-------------ESST---------------QDVTYLFRSSY---LRRISICFFC 416
            ..::...||             :|.|               |:|...|...:   .|||::....
 Frog   375 PERVFSVTQIKTIKQDDELVEIQSDTGALHRRWMIKLLNLSQEVWANFHQCFAPEYRRITLMMMA 439

  Fly   417 IWFTMNLVYYGIIL------------------------NMSSFGGN------------------- 438
            :||||:..|||:.:                        ::::|..|
 Frog   440 VWFTMSFSYYGLTVWFPDMIKHLQNIDYASRTKYFHNESVNNFNFNFTLENQVHRKGEYHNDKFI 504

  Fly   439 ----------------------------------------------------------------- 438
                                                                             
 Frog   505 GLKLKSVIFEDSLFTDCYFEDITSSNTFFKNCSFIRTMFYNTDLFDYKFINSKFTNSTFLHSKEG 569

  Fly   439 --------------VYLNSALAGLVEIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEG 489
                          :|..|.|..|..:|...|:..::.|:|:..:...:.:.:.::|........
 Frog   570 CQLDFSDDINNAYMIYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVMSCISCFFLFFGNS 634

  Fly   490 HADLLWLKITFLMMGKFTISAGNTIMPVYTAELYPTPIRNVGVG----ACNVAAGLAL-ILTPYL 549
            .:.::.|...|   |..:|::.|. :.|.|.||||:..|....|    .|.:||.|.: |.|.::
 Frog   635 ESAMIALLCLF---GGVSIASWNA-LDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFV 695

  Fly   550 SLLNKIEGHLLMTLLTAWSIFGGFVVLFLPET 581
            .:...:.    :.|.:|....|.|:.|.||||
 Frog   696 GVAKAVP----ILLASAALAVGSFLALKLPET 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	MFS_SLC22	189..579	CDD:340875	95/548 (17%)
sv2a	XP_012825002.1	synapt_SV2	1..729	CDD:130366	99/552 (18%)