DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6006 and slc22a7b.2

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	XP_001337343.1	Gene:	slc22a7b.2 / 100001838	ZFINID:	ZDB-GENE-030131-9391	Length:	556	Species:	Danio rerio

Alignment Length:	520	Identity:	138/520 - (26%)
Similarity:	230/520 - (44%)	Gaps:	34/520 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 DVIGDLMGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWC-----------QRPAQLQH 136
            |::.:|.| :|::|.::..:..|.:.....|.....:.||.....|           :..:|.:.
Zfish     5 DLLSELNG-FGRFQKMVLCINFLGRFSLGCHFLLGNFIAAIPSHHCNISSLDVDGVFENLSQEER 68

  Fly   137 MPVATWRNLSGSVDNCRRWEGIDWSQVSNETTLPSDWKTPAEMDKKLVACEK-WEYETNDNVGNT 200
            :.|.......|:..:|..:....:..:.|.:         :..|..:|.|:. |.:: |....:|
Zfish    69 LTVGVPAQEDGTPASCHMFSHPQFQLLINSS---------SSSDLPVVECQNGWHFD-NSTFIST 123

  Fly   201 WTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSS 265
            ..:||||||:|..|..:....|.|||..|....|.||..||||.||.:|.:|...|||...:.||
Zfish   124 LATQWDLVCDKRALGKLTTTIFFLGVMFGAAAFGSLSAMFGRKPMLLVSYILGMGFGLCSVLSSS 188

  Fly   266 FELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQR 330
            ..::..||...|...........:|.:|:|..:.|.:.|:.:.......:|....:||..:|::.
Zfish   189 LVMFAVLRFFSGFTITGSVIISTVLNVEWVSIEHRKLVGVIDSLAWTFGFMGFPVIAYFIRDWRW 253

  Fly   331 LQLCIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFN------GRQLPADYQLTPP 389
            |.:.|.:|.:.....|:.||||.|||:|.|:.|:....::..|..|      .|..|.|......
Zfish   254 LTVAISLPNVISIITWWWVPESARWLIVNGKADKAHYYLKKCAAMNHKKEVTARIKPEDLSKIIV 318

  Fly   390 TQESSTQDVTY--LFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIP 452
            |...| :..:|  |.|:..:||:|:.....||::..|.|||..|::.||.|:||...:.|.:|||
Zfish   319 TDRGS-RKYSYLDLVRTPKMRRLSLLTGITWFSVATVAYGISFNITGFGLNMYLTQFVYGAIEIP 382

  Fly   453 AIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEGHADLLWLKITFLMMGKFTISAGNTIMPV 517
            |.....|::.|.|:......:|:..|::............::...|..|..|....|.|..|:
Zfish   383 AKFCIYYLLDKFGRHVTQAGSLLFVGISFIINIFIPKEKTVIRTVIAVLGKGCSATSFGTVIL-- 445

  Fly   518 YTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGFVVLFLPETA 582
            ||:|||||.:|..|:|..:..|...:.:.|.:.|.|.:..:....:|...::...||...||||:
Zfish   446 YTSELYPTVVRQNGMGYTSFIARFGVSVAPLILLSNDVWSYFSQVILCFLALSAAFVAYQLPETS 510

Fly 583 582
Zfish 511 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	134/510 (26%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	105/364 (29%)
slc22a7b.2	XP_001337343.1	2A0119	12..517	CDD:273328	136/513 (27%)
slc22a7b.2	XP_001337343.1	MFS	140..504	CDD:119392	105/366 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.010