DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6006 and si:dkey-166k12.1

DIOPT Version :9

Sequence 1:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	XP_001341287.1	Gene:	si:dkey-166k12.1 / 100001249	ZFINID:	ZDB-GENE-120215-78	Length:	537	Species:	Danio rerio

Alignment Length:	517	Identity:	156/517 - (30%)
Similarity:	270/517 - (52%)	Gaps:	44/517 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 MGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQR----------PAQLQHMPVATWR 143
            :|.:||:|.|:.|.:.|.|:...||:.:|::..|.....|:.          .:.|.|:.::..|
Zfish    10 IGGFGKYQKLLYVWICLPQIFLGFHMMASVFTGATPPHRCRGSTSGMEDWTFTSNLSHVNLSISR 74

  Fly   144 NLSGSVDNCRRWEGIDWSQVSNETTLPSDWKTPAEMDKKLVACEK-WEYETNDNVGNTWTSQWDL 207
             |:|..|.|....|::.|..:|                    ||. |.| :::...:|..::|||
Zfish    75 -LAGFADACTAASGVNRSARTN--------------------CETGWVY-SHEVFQSTTVTEWDL 117

  Fly   208 VCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTL 272
            ||:|..|.::....::||:..|.::.|.::|::||:..:.:|..|||:||:......:|.:|:.|
Zfish   118 VCDKRGLSSLGSSIYMLGLLVGAVVFGAMADRYGRRFAMLVSLALQTVFGVAAAFAPNFPVYVGL 182

  Fly   273 RALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQLCIGI 337
            |.::|:....|..:..:|..|:...:.|.:||::..:.....||:::|:|:|.:|:::|||.|..
Zfish   183 RFIIGMTVSGVIINAFVLGTEWTCTQRRMLAGIFTDYFFGFGYMLLAGVAFLIRDWRKLQLAISA 247

  Fly   338 PG-IFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADYQL----TPPTQESSTQD 397
            || :|:.::| |:|.|.|||||..|.:|...::..||..|||.||...|:    :|  |..|...
Zfish   248 PGFLFIFYIW-VLPHSARWLLVNNRKEEAIDLLRKAASVNGRTLPPTVQVERYESP--QGRSKYT 309

  Fly   398 VTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAVAMYIIT 462
            |..|.|:..:|:.::..|.|||...|||||:.|.:|..|.::||...:.|||||||..:.: ::.
Zfish   310 VVDLLRTPQMRKRALILFYIWFVNVLVYYGLSLGVSDLGADLYLTQFMFGLVEIPARTLVL-VLL 373

  Fly   463 KVGKKWLFCATLICAGVACCCAAITEGHADLLWLKITFLMMGKFTISAGNTIMPVYTAELYPTPI 527
            ...:|......|:..|.||.......  ||...::....|:|||.|:|...|:.||:|||:||.:
Zfish   374 PCSRKIPLSVFLVVGGGACLLTLTLP--ADSAHVRTALAMVGKFGITASFAIIYVYSAELFPTVL 436

  Fly   528 RNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGFVVLFLPETAVRQKTDN 589
            |..|:|..::.|.:..:|.|.::||.:....:.|.:..:..:....:.|.|||||.:...|:
Zfish   437 RQTGIGVSSMFARMGGVLAPLINLLGRHTPVVPMLIFGSTPLLAAALALALPETARQPLPDS 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	152/506 (30%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	115/361 (32%)
si:dkey-166k12.1	XP_001341287.1	2A0119	11..497	CDD:273328	155/513 (30%)
si:dkey-166k12.1	XP_001341287.1	MFS	123..458	CDD:119392	112/340 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.020