DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fer2 and Atoh8

DIOPT Version :9

Sequence 1:	NP_001287359.1	Gene:	Fer2 / 41961	FlyBaseID:	FBgn0038402	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_722473.1	Gene:	Atoh8 / 71093	MGIID:	1918343	Length:	322	Species:	Mus musculus

Alignment Length:	172	Identity:	46/172 - (26%)
Similarity:	67/172 - (38%)	Gaps:	57/172 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 APLMCNSPSASSSGGGCGNAGSATPGGAGGPNPGYGSV-------------------GAATASSY 145
            |||   :|.|:........|....||     ...|.|:                   |.|||:|.
Mouse   167 APL---APPAAPQESPVRPAPPTRPG-----ESSYSSISHVIYNNHPDSSASPRKRPGEATAAST 223

  Fly   146 KM------QRQAANVRERKRIQRSAPTGYTKCSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIA 204
            ::      :|..||.|||.|:.          :|::||:.||..||.:.|.::|||:..||:|..
Mouse   224 EIKALQQTRRLLANARERTRVH----------TISAAFEALRKQVPCYSYGQKLSKLAILRIACN 278

  Fly   205 YISLLREVLQTDYDPLTYVEKCLRGEIKADRANWNTSDLTAR 246
            ||..|..:...||              .||.:|.:.|:...|
Mouse   279 YILSLARLADLDY--------------SADHSNLSFSECVQR 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer2	NP_001287359.1	HLH	148..210	CDD:278439	23/61 (38%)
Atoh8	NP_722473.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	77..96
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	101..144
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	159..221		13/61 (21%)
		Basic motif, degenerate. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00981	231..244		6/12 (50%)
		HLH	232..283	CDD:278439	23/60 (38%)
		Helix-loop-helix motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00981	245..283		16/47 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910