DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Fer2 and ASCL3

DIOPT Version :9

Sequence 1:NP_001287359.1 Gene:Fer2 / 41961 FlyBaseID:FBgn0038402 Length:283 Species:Drosophila melanogaster
Sequence 2:NP_065697.1 Gene:ASCL3 / 56676 HGNCID:740 Length:181 Species:Homo sapiens


Alignment Length:160 Identity:42/160 - (26%)
Similarity:67/160 - (41%) Gaps:49/160 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   117 GNAGSATPGGAGGPNPGYGSVGAATASSYKMQRQAANVRERKRIQRSAPTGYTKCSINSAFDELR 181
            ||.....|.....|.|.|.....:...::..:|   |.|||:|:         || :|..:.:||
Human    66 GNYSEPCPFSFPMPYPNYRGCEYSYGPAFTRKR---NERERQRV---------KC-VNEGYAQLR 117

  Fly   182 VHVPTFPYEKRLSKIDTLRLAIAYISLLREVLQTDYDPLTYVEKCLRGEIKADRANWNTSDLTAR 246
            .|:|....||||||::|||.||.||:.|:.:|..|               ||:..|         
Human   118 HHLPEEYLEKRLSKVETLRAAIKYINYLQSLLYPD---------------KAETKN--------- 158

  Fly   247 LSWINWENLGVHPGR-RTLLTSLALSSEPM 275
                       :||: .:::.:.:..::||
Human   159 -----------NPGKVSSMIATTSHHADPM 177

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fer2NP_001287359.1 HLH 148..210 CDD:278439 26/61 (43%)
ASCL3NP_065697.1 HLH 99..149 CDD:197674 26/59 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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