Protein Alignment Fer2 and ASCL1

DIOPT Version :9

• Sequence 1: NP_001287359.1
• Gene: Fer2 / 41961
• FlyBaseID: FBgn0038402
• Length: 283
• Species: Drosophila melanogaster
• Sequence 2: NP_004307.2
• Gene: ASCL1 / 429
• HGNCID: 738
• Length: 236
• Species: Homo sapiens
• Alignment Length: 195
• Identity: 46/195 - (23%)
• Similarity: 66/195 - (33%)
• Gaps: 78/195 - (40%)

  Fly   100 APLMCNSPSASSSGGGCGNAGSATP-GGAGGPN----------PGYGSVGAATASSYKMQRQAA- 152
            ||.:..:.....||||..:|..... ..:..|.          .|:|       .|...|:.||
Human    63 APQLRPAADGQPSGGGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFG-------YSLPQQQPAAV 120

  Fly   153 ---NVRERKRIQRSAPTGYTKCSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYISLLREVL- 213
               |.|||.|::          .:|..|..||.|||.....|::||::|||.|:.||..|:::|
Human   121 ARRNERERNRVK----------LVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLD 175

  Fly   214 ----------------------------------------QTDYDPLTYVEKCLRGEIKADRANW 238
                                                    :..||||:..|:.|     .|..||
Human   176 EHDAVSAAFQAGVLSPTISPNYSNDLNSMAGSPVSSYSSDEGSYDPLSPEEQEL-----LDFTNW 235

  Fly   239  238
            Human   236  235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fer2	NP_001287359.1	HLH	148..210	CDD:278439	24/65 (37%)
ASCL1	NP_004307.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..98		8/34 (24%)
		bHLH_TS_ASCL1_Mash1	115..185	CDD:381585	26/79 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810