DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer2 and Ascl2

DIOPT Version :9

Sequence 1:	NP_001287359.1	Gene:	Fer2 / 41961	FlyBaseID:	FBgn0038402	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_113691.1	Gene:	Ascl2 / 24209	RGDID:	2159	Length:	260	Species:	Rattus norvegicus

Alignment Length:	136	Identity:	41/136 - (30%)
Similarity:	57/136 - (41%)	Gaps:	26/136 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 HNSGGGAPLMCNSPSASSS---GGGCGNAGSATPGGAGG-------PNPGY------GSVGAATA 142
            |.|.|....:..:|:.::|   ||........:.|.||.       |:|..      ...||..|
  Rat    49 HFSCGAPKPVAGAPALNASLMDGGALPRLVPTSSGVAGACTARRRPPSPELLRCSRRRRSGATEA 113

  Fly   143 SSYKMQRQAANVRERKRIQRSAPTGYTKCSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYIS 207
            ||........|.|||.|::          .:|..|..||.|||.....|:|||::|||.|:.||.
  Rat   114 SSSSAAVARRNERERNRVK----------LVNLGFQALRQHVPHGGANKKLSKVETLRSAVEYIR 168

  Fly   208 LLREVL 213
            .|:.:|
  Rat   169 ALQRLL 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer2	NP_001287359.1	HLH	148..210	CDD:278439	22/61 (36%)
Ascl2	NP_113691.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	85..126		10/40 (25%)
		HLH	134..176	CDD:197674	19/41 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	191..239
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810