DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer2 and Ptf1a

DIOPT Version :9

Sequence 1:	NP_001287359.1	Gene:	Fer2 / 41961	FlyBaseID:	FBgn0038402	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_061279.2	Gene:	Ptf1a / 19213	MGIID:	1328312	Length:	324	Species:	Mus musculus

Alignment Length:	130	Identity:	61/130 - (46%)
Similarity:	74/130 - (56%)	Gaps:	25/130 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 GAPLMC--NSPSASSSGGGCGNAGSATPGG-AGGPNPGYGSVGAATA-------SSYKMQ--RQA 151
            ||||..  .||.:..|......|...:||. .||.|   |:..||.|       |..::|  |||
Mouse   103 GAPLAAFPYSPGSPPSCLAYPCAAVLSPGARLGGLN---GAAAAAAARRRRRVRSEAELQQLRQA 164

  Fly   152 ANVRERKRIQRSAPTGYTKCSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYISLLREVLQTD 216
            ||||||:|:|          |||.||:.||.|:||.||||||||:|||||||.||:.|.|::|.|
Mouse   165 ANVRERRRMQ----------SINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQAD 219

Fly 217 216
Mouse 220 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer2	NP_001287359.1	HLH	148..210	CDD:278439	39/63 (62%)
Ptf1a	NP_061279.2	HLH	162..217	CDD:238036	40/64 (63%)
Ptf1a	NP_061279.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	302..324
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2562
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840