DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer2 and Ascl1

DIOPT Version :9

Sequence 1:	NP_001287359.1	Gene:	Fer2 / 41961	FlyBaseID:	FBgn0038402	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_032579.2	Gene:	Ascl1 / 17172	MGIID:	96919	Length:	231	Species:	Mus musculus

Alignment Length:	197	Identity:	50/197 - (25%)
Similarity:	69/197 - (35%)	Gaps:	82/197 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 APLMCNSPSASS--SGGGCGNAGSATP-GGAGGPN----------PGYGSVGAATASSYKMQRQA 151
            ||.:  ||.|.|  ||||..:|..... ..:..|.          .|:|       .|...|:.|
Mouse    58 APQL--SPVADSQPSGGGHKSAAKQVKRQRSSSPELMRCKRRLNFSGFG-------YSLPQQQPA 113

  Fly   152 A----NVRERKRIQRSAPTGYTKCSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYISLLREV 212
            |    |.|||.|::          .:|..|..||.|||.....|::||::|||.|:.||..|:::
Mouse   114 AVARRNERERNRVK----------LVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQL 168

  Fly   213 L-----------------------------------------QTDYDPLTYVEKCLRGEIKADRA 236
            |                                         :..||||:..|:.|     .|..
Mouse   169 LDEHDAVSAAFQAGVLSPTISPNYSNDLNSMAGSPVSSYSSDEGSYDPLSPEEQEL-----LDFT 228

  Fly   237 NW 238
            ||
Mouse   229 NW 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer2	NP_001287359.1	HLH	148..210	CDD:278439	24/65 (37%)
Ascl1	NP_032579.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	39..92		12/35 (34%)
		HLH	129..171	CDD:197674	18/41 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810