DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer2 and AgaP_AGAP003739

DIOPT Version :9

Sequence 1:	NP_001287359.1	Gene:	Fer2 / 41961	FlyBaseID:	FBgn0038402	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	XP_310271.7	Gene:	AgaP_AGAP003739 / 1271473	VectorBaseID:	AGAP003739	Length:	259	Species:	Anopheles gambiae

Alignment Length:	293	Identity:	174/293 - (59%)
Similarity:	195/293 - (66%)	Gaps:	55/293 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RNQLPDSSSSPPISHLPFHNFDDDLINDLPSCIYAGQHQGGGATG-GGGGSGGGGGSSG------ 60
            |:||||||||||:|.:.||:|||:|:.|||||:||..||...|.| ||.||...|.|:|
Mosquito     6 RSQLPDSSSSPPLSGIGFHSFDDELMADLPSCVYAQHHQLNTAPGNGGAGSSSAGHSAGHSGHTG 70

  Fly    61 -----LRLSSNNLRHIQQHYMQHSGENLLDSSTNPMGVHNSGGGAPLMCNSPSASSSGGGCGNAG 120
                 |||:..::|.:|..|:.|:  ..|||||.|               |||.|::.|    ..
Mosquito    71 NAPPNLRLNPTSIRQMQHQYLHHT--ECLDSSTPP---------------SPSLSTTMG----TH 114

  Fly   121 SATPGGAGGPNPGYGSVGAATASSYKMQRQAANVRERKRIQRSAPTGYTKCSINSAFDELRVHVP 185
            ...|       |.|.          |||||..|||||||:.||||.|    ||||||||||||||
Mosquito   115 PYNP-------PPYN----------KMQRQQTNVRERKRMMRSAPNG----SINSAFDELRVHVP 158

  Fly   186 TFPYEKRLSKIDTLRLAIAYISLLREVLQTDYDPLTYVEKCLRGEIKADRANWNTSDLTARLSWI 250
            |||||||||||||||||||||:||||||:.|||||||||||||||||||||:|||||||||||||
Mosquito   159 TFPYEKRLSKIDTLRLAIAYIALLREVLEADYDPLTYVEKCLRGEIKADRAHWNTSDLTARLSWI 223

  Fly   251 NWENLGVHPGRRTLLTSLALSSEPMCGAHCGMP 283
            |||||||||||||:||||||.|....|| ||.|
Mosquito   224 NWENLGVHPGRRTILTSLALGSSESMGA-CGPP 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer2	NP_001287359.1	HLH	148..210	CDD:278439	51/61 (84%)
AgaP_AGAP003739	XP_310271.7	HLH	125..183	CDD:278439	51/61 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	132	1.000	Domainoid score	I10340
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15337
Inparanoid	1	1.050	299	1.000	Inparanoid score	I5086
OMA	1	1.010	-	-		QHG26792
OrthoDB	1	1.010	-	-		D1185741at2759
OrthoFinder	1	1.000	-	-		FOG0010640
OrthoInspector	1	1.000	-	-		oto111098
Panther	1	1.100	-	-	LDO	PTHR23349
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3328
TreeFam	0	0.000	Not matched by this tool.
	11	11.080