DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Fer2 and ASCL4

DIOPT Version :9

Sequence 1:NP_001287359.1 Gene:Fer2 / 41961 FlyBaseID:FBgn0038402 Length:283 Species:Drosophila melanogaster
Sequence 2:NP_982260.3 Gene:ASCL4 / 121549 HGNCID:24311 Length:172 Species:Homo sapiens


Alignment Length:135 Identity:38/135 - (28%)
Similarity:60/135 - (44%) Gaps:31/135 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    88 TNPMGVHNSGGGAP--------LMCNSPSASSSGGGCGNAGSATPGGAGGPNPGYGSVGAATASS 144
            |.|:||..:..|.|        |..::.....:..||.......|          ..:.:|...:
Human    18 TAPLGVPGTLPGLPRRDPLRVALRLDAACWEWARSGCARGWQYLP----------VPLDSAFEPA 72

  Fly   145 YKMQRQAANVRERKRIQRSAPTGYTKCSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYISLL 209
            :..:|   |.|||:|:         :| :|..:..||.|:|....:|||||::|||.||.||..|
Human    73 FLRKR---NERERQRV---------RC-VNEGYARLRDHLPRELADKRLSKVETLRAAIDYIKHL 124

  Fly   210 REVLQ 214
            :|:|:
Human   125 QELLE 129

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fer2NP_001287359.1 HLH 148..210 CDD:278439 24/61 (39%)
ASCL4NP_982260.3 bHLH_SF 66..129 CDD:412148 27/75 (36%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 144..172
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

Return to query results.
Submit another query.