DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer2 and atoh8

DIOPT Version :9

Sequence 1:	NP_001287359.1	Gene:	Fer2 / 41961	FlyBaseID:	FBgn0038402	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	XP_002937330.2	Gene:	atoh8 / 100490889	XenbaseID:	XB-GENE-877027	Length:	246	Species:	Xenopus tropicalis

Alignment Length:	226	Identity:	63/226 - (27%)
Similarity:	92/226 - (40%)	Gaps:	52/226 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 NFDDDL-INDLPSCIYAGQHQG--GGATG----GGG-----GSGGGGGSSGLRLSSNNLRHIQQH 74
            :|..|| :::.|:....||.|.  ||..|    ||.     .:|...|..|| :.|..|...||.
Frog    41 SFKVDLKVDEAPAEGRTGQQQELLGGRAGERVLGGDVLDLRNNGLYPGKKGL-MKSRELEGQQQP 104

  Fly    75 YMQHSGENLLDSSTNPMGVHNSGGGAPLMCNSPSASSSGGGCGNAGSATPGGAGGPNPGYGSVGA 139
            .|.     :..:...|...:.....||.   ||..           ||:|....|...|   |.:
Frog   105 RMV-----ICPARPPPETPYLPAPQAPY---SPDP-----------SASPRNRLGETAG---VNS 147

  Fly   140 ATASSYKMQRQAANVRERKRIQRSAPTGYTKCSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIA 204
            ...:..:.:|..||.|||.|:.          :|::||:.||..||.:.|.::|||:..||:|..
Frog   148 EIKAIQQTRRLLANARERTRVH----------TISAAFEALRKQVPCYSYGQKLSKLAILRIACN 202

  Fly   205 YISLLREVLQTDY----DPLTY---VEKCLR 228
            ||..|..:...||    ..|::   ||:|.|
Frog   203 YILSLARLADLDYSVDHSNLSFPECVEQCTR 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer2	NP_001287359.1	HLH	148..210	CDD:278439	23/61 (38%)
atoh8	XP_002937330.2	bHLH_TS_ATOH8	149..216	CDD:381427	25/76 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910