DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer2 and ascl1

DIOPT Version :9

Sequence 1:	NP_001287359.1	Gene:	Fer2 / 41961	FlyBaseID:	FBgn0038402	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	XP_002944648.3	Gene:	ascl1 / 100490701	XenbaseID:	XB-GENE-1032967	Length:	199	Species:	Xenopus tropicalis

Alignment Length:	170	Identity:	43/170 - (25%)
Similarity:	73/170 - (42%)	Gaps:	34/170 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 SSGLRLSSNNL--RHIQQHYMQHSGENLLDSSTNPMGVHNSGGGAPLMCNSPSASSSGGGCGNAG 120
            :|...:..:||  :..|||::|.:.....:...:|...|.:.....:. ...|:|.....|....
Frog     3 NSAANIMESNLSGQQQQQHFLQPACFFPQNVQLSPAEEHEAAKPKQIK-RQRSSSPELMRCKRRL 66

  Fly   121 SATPGGAGGPNPGYGSVGAATASSYKMQRQAA----NVRERKRIQRSAPTGYTKCSINSAFDELR 181
            :.|         |:|       .|...|:.||    |.|||.|::          .:|..|..||
Frog    67 NFT---------GFG-------YSLPQQQPAAVARRNERERNRVK----------LVNLGFATLR 105

  Fly   182 VHVPTFPYEKRLSKIDTLRLAIAYISLLREVLQTDYDPLT 221
            .|||.....|::||::|||.|:.||..|:::|. ::|.::
Frog   106 EHVPNGAANKKMSKVETLRSAVEYIRALQQLLD-EHDAVS 144

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer2	NP_001287359.1	HLH	148..210	CDD:278439	24/65 (37%)
ascl1	XP_002944648.3	bHLH_TS_ASCL1_Mash1	78..148	CDD:381585	27/78 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910