DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5916 and RABGAP1L

DIOPT Version :9

Sequence 1:NP_001287357.1 Gene:CG5916 / 41960 FlyBaseID:FBgn0038401 Length:330 Species:Drosophila melanogaster
Sequence 2:NP_001353375.1 Gene:RABGAP1L / 9910 HGNCID:24663 Length:1051 Species:Homo sapiens


Alignment Length:249 Identity:68/249 - (27%)
Similarity:121/249 - (48%) Gaps:15/249 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 KWEAILQQNTDLTQVDAKLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKE 109
            ||      :::|......|...::.|:|...|.:||..::|....|... |.:|.|:..:...:.
Human   519 KW------HSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAML-DRYRILITKDSAQES 576

  Fly   110 ISDSISIDLPRTFPDNIHFDMK----KQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEE 170
            :   |:.|:.||||.:.:|...    ::.||.|..||:.::.|:|||||.:::|.:||:...:|:
Human   577 V---ITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQ 638

  Fly   171 KSFWLLKHIVENIVPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICI 235
            ....|:|.:.:..:...:.:|..:|.........|:..::|.::.|..:|.|...:.||:||:.:
Human   639 AFCVLVKIMYDYGLRDLYRNNFEDLHCKFYQLERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTL 703

  Fly   236 FAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAILGCDDIAALANLFR 289
            |....|:..|..|.|.:..||..|:|..||.:..|.|..:|..|...|| ..||
Human   704 FTAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGAL-KFFR 756

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5916NP_001287357.1 TBC 67..276 CDD:214540 58/212 (27%)
RABGAP1LNP_001353375.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..52
PTB_Rab6GAP 129..257 CDD:269922
DUF3694 290..421 CDD:315198
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 461..503
RabGAP-TBC 541..744 CDD:306939 56/206 (27%)
DUF3084 800..>1018 CDD:331293
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5210
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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