DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and Usp6nl

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_852064.2	Gene:	Usp6nl / 98910	MGIID:	2138893	Length:	842	Species:	Mus musculus

Alignment Length:	323	Identity:	88/323 - (27%)
Similarity:	150/323 - (46%)	Gaps:	29/323 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 DEYGFKRGDHFDYNNYSKFMDGYLKTLTRRRMKWEAILQ-----QNTDLTQVDAKLKRYIRKGIP 72
            |.:||...:...|:|.:  .|...:....|..||..:|:     :||:      |..|.|.||||
Mouse    69 DRFGFLHEEELPYHNAA--ADRQKQLEIERTSKWLKMLKKWERYKNTE------KFHRRIYKGIP 125

  Fly    73 GPYRPDVWMKISGAAAAQRRSPDLFRNLL-RTEPFDKEISDSISIDLPRTFPDNIHF----DMKK 132
            ...|.:||..:......:..:.||:..|. |......:|. .|.:|:.|||.|:|.|    .:|:
Mouse   126 LQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIR-QIDLDVNRTFRDHIMFRDRYGVKQ 189

  Fly   133 QRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEEKSFWLLKHIVENIVPQYHSH-----NM 192
            |.|:::|.||:.:|.:||||||::.|..|||:.. :||.:||.|..:...  |::..|     ..
Mouse   190 QSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYM-NEEDAFWALVKLFSG--PKHAMHGFFVQGF 251

  Fly   193 ANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLRIWDCVFAEGY 257
            ..|||......:::.:.:..:.:|:|:..:.......|||...|.:..|....|||||....||.
Mouse   252 PKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFRLNLRIWDIYIFEGE 316

  Fly   258 KIVFRAALTMFVTHKNAILGCDDIAALANLFRDTMIQDNIVTDCHGFVEAMFSL-RLKRSELE 319
            :::...:.|:...||..::.. .:..|....::|:.:|....|.....:...|: .|||::|:
Mouse   317 RVLTAMSYTILKLHKKHLMKL-SMEELVEFLQETLAKDFFFEDDFVIEQLQVSMAELKRAKLD 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	65/218 (30%)
Usp6nl	NP_852064.2	TBC	120..335	CDD:214540	65/218 (30%)
Usp6nl	NP_852064.2	SPRR2	<590..642	CDD:291486
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810