DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and GYP5

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_015075.1	Gene:	GYP5 / 855827	SGDID:	S000006170	Length:	894	Species:	Saccharomyces cerevisiae

Alignment Length:	239	Identity:	67/239 - (28%)
Similarity:	120/239 - (50%)	Gaps:	13/239 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 RMKWEAILQQNTDLTQVDA----KLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRT 103
            ::.|....|...|...|.:    .|:.::..|||...|..:|..:  |.:..|...|::..||.|
Yeast   420 KIDWSFWTQVVNDYATVASNEPENLEAHVTNGIPPQIRGIIWQLM--ANSKSREMEDIYETLLDT 482

  Fly   104 EPFDKEISDSISIDLPRTFPDNIHFDMKKQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDD 168
            |...:.   :|..||.||   ....:.|.:.||.::..|:.::.||||.||:.:||..|||..::
Yeast   483 ECLHEA---TIRRDLRRT---KFVAEDKMESLYKVIKVYSVYDPDVGYTQGMGFIAAPLLINCEN 541

  Fly   169 EEKSFWLLKHIVENI-VPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWF 232
            |.:||.||..:::|. :.:.....|..|:..|..|..|:....|::...:...|:...:.|::||
Yeast   542 EAESFGLLVGLMKNYGLRELFLPGMPGLMLMLYQFDRLLEEHSPSLYNRLIREGISSTMYATQWF 606

  Fly   233 ICIFAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAIL 276
            :..||...|:|.||||:|.||.||.:::.:.|:.:.:.::..::
Yeast   607 LTFFAYKFPLEFVLRIFDIVFVEGIEVLLKFAVNLMLKNEETLV 650

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	62/209 (30%)
GYP5	NP_015075.1	COG5210	154..737	CDD:227535	67/239 (28%)
GYP5	NP_015075.1	SMC_prok_B	726..>891	CDD:274008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810