DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and tbc1d30

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	XP_017947631.1	Gene:	tbc1d30 / 734068	XenbaseID:	XB-GENE-5823666	Length:	942	Species:	Xenopus tropicalis

Alignment Length:	344	Identity:	88/344 - (25%)
Similarity:	156/344 - (45%)	Gaps:	74/344 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 AILQQNTDLTQVDAKLK---------------------------RYIRKGIPGPYRPDVWMKISG 85
            |.||..:...:||.|||                           ..:..|||..:|..||:.::
Frog   209 ACLQAVSQKRRVDTKLKFTLEPSLGQNGFQQFFCLQWYDALKAVARLPTGIPKEWRKRVWLTLA- 272

  Fly    86 AAAAQRRSPDLFRNLL--------------RTEPFDKEISDSISIDLPRTFPDNI---HFDMKKQ 133
                     |.:.:.:              |:.|.|..:...|..||.||...:.   ..:..:.
Frog   273 ---------DHYLHSISIDWDKTMRFTFNDRSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRV 328

  Fly   134 RLYNILIAYAHHNRDVGYCQGLNYIAGLLL-IVTDDEEKSFWLLKHIVENIVP-QYHSHNMANLL 196
            .|..:|:|||..|:.:|||||.|.:|.|:| ::..:|..:..::.::::.::| .|.::|:..|.
Frog   329 VLKRVLLAYARWNKTIGYCQGFNILAALILEVMEGNEGDALKVMIYLIDKVLPDSYFANNLRALS 393

  Fly   197 RDLAVFRELVIRRIPAVNRHVDNL----------GLPYP---VIASKWFICIFAEVLPVETVLRI 248
            .|:||||:||..::|.:::|:|.|          |...|   |...:||:.:||..||..|||:|
Frog   394 VDMAVFRDLVRMKLPELSQHLDVLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKI 458

  Fly   249 WDCVFAEGYKIVFRAALTMFVTHKNAILGC---DDIAALANLFRDTMIQDNIVTDCHGFVEAMFS 310
            ||.||.||.:|:.|.:|.::......|..|   ||..:........|::|::: |.:..::.::|
Frog   459 WDSVFFEGSEILLRVSLAIWAKLGEQIECCQNSDDFYSTMGRLTQEMLEDSLI-DSNELMQTVYS 522

  Fly   311 L-RLKRSELESLRKVAVLN 328
            : :....:|..||:....|
Frog   523 MAQFPFPQLAELREKYTYN 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	68/240 (28%)
tbc1d30	XP_017947631.1	TBC	258..477	CDD:214540	68/228 (30%)
tbc1d30	XP_017947631.1	DUF4682	646..789	CDD:374060
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920