DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5916 and tbc1d2b

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	XP_012822167.2	Gene:	tbc1d2b / 734055	XenbaseID:	XB-GENE-5932742	Length:	944	Species:	Xenopus tropicalis

Alignment Length:	327	Identity:	96/327 - (29%)
Similarity:	157/327 - (48%)	Gaps:	47/327 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LKTLTRRR-------MKWEAILQQNTDLTQV-DAKLKRYIRKGIPGPYRPDVW--------MKIS 84
            ||||:...       :||:.......:.... ..:||..:|.|||..:|..:|        .|:.
Frog   601 LKTLSLTENQEISNVVKWDNYFASTVNREMACSPELKALVRNGIPHEHRSRMWKWFTNLHIKKLK 665

  Fly    85 GAAAAQRRSPDLFRNLLRTEPFDKE--ISDSISIDLPRTFPDNIHFDMKK----QRLYNILIAYA 143
            ..||     |..|::||: ...:|:  .|..|.:||.||.|:|.|:....    |:|.|:|:||:
Frog   666 DEAA-----PGYFQSLLQ-NALEKQNPASKQIELDLMRTLPNNKHYTSPTSEGIQKLRNVLLAYS 724

  Fly   144 HHNRDVGYCQGLNYIAGLLLIVTDDEEKSFWLLKHIVENIVPQ-YHSHNMANLLRDLAVFRELVI 207
            ..|.|:|||||:|.:|.:.|:..|.|: :||.|..|||..:|: |::..:.....|..||::|:.
Frog   725 WRNPDIGYCQGINRLAAIALLYLDQED-AFWCLVTIVEAFMPRDYYTKTLLGSQVDQRVFKDLMN 788

  Fly   208 RRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHK 272
            .::|.:..|.:...:.|.:|...||:.:|.:.:..:.:.||||.:..||.|::||.||.:|...:
Frog   789 EKLPRLCAHFEQYKVDYTLITFNWFLVVFVDSVVSDILFRIWDSLLYEGSKVIFRFALGLFKYKE 853

  Fly   273 NAILGCDDIAALANLFR-------DTMIQDNIV-TDCHGF---------VEAMFSLRLKRSELES 320
            ..||...|..::....|       |.....||. .|.:.|         ...:..:||:.||||:
Frog   854 EEILKLQDSMSIFKYLRYFSRTILDARKLCNIAFVDMNPFPLRQIRNRRTYHLEKVRLELSELEA 918

  Fly   321 LR 322
            :|
Frog   919 IR 920

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	72/223 (32%)
tbc1d2b	XP_012822167.2	PH_TBC1D2A	34..134	CDD:269966
		BAR	313..>425	CDD:416402
		Smc	<324..532	CDD:224117
		TBC	640..857	CDD:214540	72/223 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920