Protein Alignment CG5916 and TBC1D3H

DIOPT Version :10

• Sequence 1: NP_650524.1
• Gene: CG5916 / 41960
• FlyBaseID: FBgn0038401
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: XP_011523474.1
• Gene: TBC1D3H / 729877
• HGNCID: 30708
• Length: 610
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 84/338 - (24%)
• Similarity: 135/338 - (39%)
• Gaps: 59/338 - (17%)

  Fly     2 DATASSKFSDVDEYGFKRGDHFDYNNYSKFMDGYLK--TLTRRRMKWEAILQQNTDLTQVDAKLK 64
            :.:..||:.|:      .||...|.:..|.:|...|  .:..|...|..:|  ||:    :.|||
Human   132 EISRKSKWVDM------LGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLL--NTE----EMKLK 184

  Fly    65 RYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKEISDSISIDLPRTFPDNIHFD 129
            .      ||.|:   .||..|     :||.:..:.:      |::||.::...:  .|.|  .:.
Human   185 N------PGRYQ---IMKEKG-----KRSSEHIQRI------DRDISGTLRKHM--FFRD--RYG 225

  Fly   130 MKKQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEEKSFWLLKHIV---ENIVPQYHSHN 191
            .|::.|.:||:||..:|.:||||:.|::||.|.|:.. .||.:||.|..::   .:.:..:||.|
Human   226 TKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYL-PEEDAFWALVQLLASERHSLQGFHSPN 289

  Fly   192 MANL--LRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLRIWDCVFA 254
            ...:  |:|..  ..:|....|....|.|...|..........|.|..:.:.:...||:||....
Human   290 GGTVQGLQDQQ--EHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLV 352

  Fly   255 EGYKIVFRAALTMFVTHKNAIL---GCDDIAALANLFRDTMIQDNIVTDCHGFVEAMFSLRLKRS 316
            ||.:.:.......|...:..:.   .|...|...|.|.||..:|......|          |:.|
Human   353 EGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKH----------LRAS 407

  Fly   317 ELESLRKVAVLNP 329
            ..:..||...|.|
Human   408 MKKLTRKQGDLPP 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_650524.1	TBC	67..276	CDD:214540	53/213 (25%)
TBC1D3H	XP_011523474.1	TBC	160..373	CDD:214540	62/245 (25%)
		PHA03381	<417..>529	CDD:177618	2/4 (50%)