DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and Grtp1

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001355787.1	Gene:	Grtp1 / 66790	MGIID:	1914040	Length:	359	Species:	Mus musculus

Alignment Length:	343	Identity:	140/343 - (40%)
Similarity:	203/343 - (59%)	Gaps:	27/343 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ASSKFSDVDEYGFKRGDHFDYNNYSKFMDGYLKTLTRRRMKWEAILQQNTDLTQVDAKLKRYIRK 69
            |.::...:|.|||:|.:.|||..|.:|...||..||:|.:||..:|:.|..:.: ...:|||:||
Mouse    10 ARARVPRIDPYGFERPEDFDYAAYEEFFSTYLVILTKRAIKWSKLLKGNGGVRK-SVTVKRYVRK 73

  Fly    70 GIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKEISDSISIDLPRTFPDNIHF-----D 129
            |||..:|..|||.:|||.|...:||..:..||..|. ...:.::|..||.||||||:.|     .
Mouse    74 GIPLEHRARVWMAVSGAQARMDQSPGYYHRLLEGES-SSSLDEAIRTDLNRTFPDNVMFRKTADP 137

  Fly   130 MKKQRLYNILIAYAHHNRDVGYCQ-----------------GLNYIAGLLLIVTDDEEKSFWLLK 177
            ..::.|||:|:||..||.||||||                 |:|:|||.|:::|.:||:|||||.
Mouse   138 CLQKTLYNVLLAYGLHNPDVGYCQCCAQKPGSSAGLRSSLTGMNFIAGYLILITKNEEESFWLLD 202

  Fly   178 HIVENIVPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPV 242
            .:|..|:|.|:|..|..|..|..|..|||..::|||...:|..|:.:.::.|:||||:|.::|||
Mouse   203 ALVGRILPDYYSPAMLGLKTDQEVLAELVRMKLPAVAALMDGHGVLWTLLVSRWFICLFVDILPV 267

  Fly   243 ETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAILGCDDIAALANLFRDTMIQDNIVTDCHGFVEA 307
            |||||||||:|.||.||:||.|||:...|:..||....|..:.:.|:. :.:.:.||:||.|::.
Mouse   268 ETVLRIWDCLFNEGSKIIFRVALTLIKQHQEFILEASSIPDICDKFKQ-ITKGDFVTECHAFMQK 331

  Fly   308 MFSL--RLKRSELESLRK 323
            :||.  .|..:.:..|||
Mouse   332 IFSEPGSLSMTTITRLRK 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	102/230 (44%)
Grtp1	NP_001355787.1	TBC	71..301	CDD:214540	102/230 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	60	1.000	Domainoid score	I10559
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H84592
Inparanoid	1	1.050	259	1.000	Inparanoid score	I3117
Isobase	1	0.950	-	0	Normalized mean entropy	S2150
OMA	1	1.010	-	-		QHG53652
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	1	1.000	-	-		FOG0003486
OrthoInspector	1	1.000	-	-		oto93505
orthoMCL	1	0.900	-	-		OOG6_100958
Panther	1	1.100	-	-	LDO	PTHR22957
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R540
SonicParanoid	1	1.000	-	-		X2377
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.820