DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and Tbc1d15

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	XP_006514020.1	Gene:	Tbc1d15 / 66687	MGIID:	1913937	Length:	688	Species:	Mus musculus

Alignment Length:	288	Identity:	54/288 - (18%)
Similarity:	108/288 - (37%)	Gaps:	48/288 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DATASSKFSDVDEYGFKRGDHFDYNNYSKFMDGYLKTLTRRR-----MKWEAILQQNTDLTQVDA 61
            ||....|.:..:|.||:.....|...         :.:.:||     .:|...|.....|..|::
Mouse   282 DAIPGLKINQQEEPGFEVITRIDLGE---------RPVVQRREPVSLEEWNKSLDPEGRLVAVES 337

  Fly    62 KLKRYIRKGIPGPYRPDVWMKISG-----------AAAAQRRSPDLFRNLLRTEPFDKEISDS-- 113
            ..::..|.|:....|...|..:.|           ....::::.:.||..|:.    |.:|::
Mouse   338 MKQKIFRGGLSHSLRKQAWKFLLGYFPWDSTKEERTQLQKQKTDEYFRMKLQW----KSVSEAQE 398

  Fly   114 ------------ISIDLPRTFPDNIHFDMKKQ----RLYNILIAYAHHNRDVGYCQGLNYIAGLL 162
                        |..|:.||...|..::.:..    .|::||:.|..::.|:||.||::.:...|
Mouse   399 KRNSRLRDYRSLIEKDVNRTDRTNKFYEGQDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPL 463

  Fly   163 LIVTDDEEKSFWLLKHIVENIVPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVI 227
            |.|.::|..:||.....::. :.|.....|..:...|.....|:.........::::....|...
Mouse   464 LYVMENEVDAFWCFASYMDQ-MHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYF 527

  Fly   228 ASKWFICIFAEVLPVETVLRIWDCVFAE 255
            ..:|.:..|........:||:|:.::.|
Mouse   528 CFRWLLIRFKREFSFLDILRLWEVMWTE 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	41/218 (19%)
Tbc1d15	XP_006514020.1	DUF3548	10..211	CDD:371881
Tbc1d15	XP_006514020.1	TBC	343..578	CDD:214540	41/218 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810