DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and tbc1d30

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	XP_021331078.1	Gene:	tbc1d30 / 569334	ZFINID:	ZDB-GENE-030131-2064	Length:	1063	Species:	Danio rerio

Alignment Length:	339	Identity:	87/339 - (25%)
Similarity:	155/339 - (45%)	Gaps:	75/339 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KTLTRRRMKWE-------AILQQNTDLTQVDAKLKRYIRK----------------------GIP 72
            |...|.|.|::       |.||..:...:||.:||..|..                      |||
Zfish   177 KRKDRLRQKFQKNCDIVTACLQAVSQKRRVDTRLKFTIEPSLGKNGFQQWYDALKAVARLPVGIP 241

  Fly    73 GPYRPDVWMKISGAAAAQRRSPDLFRNLL--------------RTEPFDKEISDSISIDLPRTFP 123
            ..:|..||:.::          |.:.:.:              |:.|.|..:...|..||.||..
Zfish   242 KEWRKRVWLTLA----------DQYLHSISIDWEKTMRFAFNDRSNPDDDSLGIQIVKDLHRTGC 296

  Fly   124 DNI---HFDMKKQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTD-DEEKSFWLLKHIVENIV 184
            .:.   ..:..:..|..:|:|||..|:.||||||.|.:|.|:|.||: :|..:..::.::::.::
Zfish   297 SSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNVLAALILEVTEGNEGDALKVMIYLIDKVL 361

  Fly   185 P-QYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNL--------GLPYP-----VIASKWFICI 235
            | .|.::|:..|..|:||||:|:..::|.:::|:.:|        |..|.     |...:||:.:
Zfish   362 PDSYFANNLRALSVDMAVFRDLLRLKLPELSQHLHHLQKVANREAGGSYEPPLTNVFTMQWFLTM 426

  Fly   236 FAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAILGC---DDIAALANLFRDTMIQDNI 297
            ||..||..|||:|||.||.||.:::.|.||.::......|..|   |:..::.......|::..:
Zfish   427 FATCLPHHTVLKIWDSVFFEGSEMLLRVALAIWAKLGERIEECQTADEFYSIMGCLTQEMLEHKL 491

  Fly   298 VTDCHGFVEAMFSL 311
            : |.:..::.::|:
Zfish   492 I-DSNELMQTVYSM 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	70/262 (27%)
tbc1d30	XP_021331078.1	TBC	239..458	CDD:214540	69/228 (30%)
		DUF4682	625..775	CDD:318030
		HrpB7	733..>820	CDD:330448
		Herpes_BLLF1	<825..>973	CDD:330317
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820