DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and tbc1d10ab

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	XP_691101.1	Gene:	tbc1d10ab / 562628	ZFINID:	ZDB-GENE-081105-145	Length:	479	Species:	Danio rerio

Alignment Length:	332	Identity:	97/332 - (29%)
Similarity:	148/332 - (44%)	Gaps:	55/332 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ASSKFSD------------VDEYGF------KRGDHFDYNNYSKFMDGYLKTLTRRRMKWEAILQ 51
            :||:.||            .|:|||      ..|::.|        |.....|.:|..||..:|
Zfish    30 SSSRGSDSELNGFANTEVQPDKYGFIGGAQQTAGENSD--------DIPPDVLRQREAKWLDML- 85

  Fly    52 QNTD--LTQVDAKLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKEISDSI 114
            .|.|  :.:...|:|...:||||...|...|:.:||....:.::|..|:. |.::|.|.:..|.|
Zfish    86 NNWDKWMAKKHKKVKLRCQKGIPPSLRGRAWLYLSGGKVKKEQNPGKFKE-LDSQPGDPKWLDVI 149

  Fly   115 SIDLPRTFPDNIHFDMK----KQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEEKSFWL 175
            ..||.|.||.:..|..:    :|.|:.:|.||..|..:.||||....||.:||:....|: :||.
Zfish   150 EKDLHRQFPFHEMFVARGGHGQQDLFRVLKAYTLHRPEEGYCQAQAPIAAVLLMHMPAED-AFWG 213

  Fly   176 LKHIVENIVPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICIFAEVL 240
            |..|.|..:|.|:|..:..:..|..:...|:.|..|..:||:....:...:..::||:|.|:..|
Zfish   214 LVQICEKYLPGYYSAGLEAIQLDGEILFALLKRVSPVAHRHLKKYKIDPILYMTEWFMCAFSRTL 278

  Fly   241 PVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAILGCDDIAALANLFRDTMIQDNIVTDCHGFV 305
            |..:|||:||..|.||.||:||..|.:.    ..:||..:                .:..|.|..
Zfish   279 PWASVLRVWDMFFCEGVKIIFRVGLVLL----KCMLGSPE----------------KLKACQGQY 323

  Fly   306 EAMFSLR 312
            |.|..||
Zfish   324 ETMELLR 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	69/212 (33%)
tbc1d10ab	XP_691101.1	TBC	105..307	CDD:214540	69/207 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R540
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940