DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and rabgap1l

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	XP_021325262.1	Gene:	rabgap1l / 555272	ZFINID:	ZDB-GENE-050208-389	Length:	1069	Species:	Danio rerio

Alignment Length:	251	Identity:	75/251 - (29%)
Similarity:	121/251 - (48%)	Gaps:	14/251 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 WEAILQ--QNTDLTQVDAKLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDK 108
            |..||.  |...||:... |...::.|||...|.:||..:||....|... :.:|.|:..|...:
Zfish   537 WGGILNRWQGNLLTRPKG-LSALVKPGIPEALRAEVWQLLSGCHNDQALL-EQYRILITKESAQE 599

  Fly   109 EISDSISIDLPRTFPDNIHFDMK----KQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDE 169
            .:   |:.|:.||||.:.:|...    :..||.|..||:.::.::|||||.:::|.:||:.. .|
Zfish   600 AV---ITRDIHRTFPAHDYFKDSGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHM-PE 660

  Fly   170 EKSFWLLKHIVENI-VPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFI 233
            |::|.:|..|:.|. :.:.:.:|..:|.........|:...:|.:..|...|.|...:.||:||:
Zfish   661 EQAFCVLVKIMFNYGLRELYRNNFEDLHCKFYQLERLLQELLPDLWSHFQELNLEAHMYASQWFL 725

  Fly   234 CIFAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAILGCDDIAALANLFR 289
            .:|....|:..|..|.|.:..||..|:|..||.:..|.|..:|..|...|| ..||
Zfish   726 TLFTAKFPLCMVFHITDLLLCEGLNIIFNVALALLKTSKEDLLQADFEGAL-KFFR 780

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	62/213 (29%)
rabgap1l	XP_021325262.1	PTB_Rab6GAP	157..285	CDD:269922
		DUF3694	319..450	CDD:315198
		RabGAP-TBC	565..768	CDD:306939	59/207 (29%)
		SMC_N	784..>1042	CDD:330553
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810