DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and si:dkeyp-19e1.3

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	XP_005170766.1	Gene:	si:dkeyp-19e1.3 / 553000	ZFINID:	ZDB-GENE-081104-56	Length:	736	Species:	Danio rerio

Alignment Length:	341	Identity:	82/341 - (24%)
Similarity:	152/341 - (44%)	Gaps:	62/341 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ASSKFSDVDEY--GFKRGDHF------DYNNYSKFMDGY-------LKTLT-----------RRR 43
            |..:...:::|  |.:.|.|.      ||:.: ||.|.:       |.|.|           .|.
Zfish    10 AEERADIIEKYEKGRQEGVHINPWEDGDYSIF-KFTDRFGFLHEEELPTPTAVEEKYKLQEMERE 73

  Fly    44 MKWEAILQQNTDLTQVDAKLKRYIRKGIPGPYRPDVW---MKISGAAAAQRRSPDLFRNLLRTEP 105
            .||..::::.......:..:|| :.||||...|...|   :.:.....|..|..:..:.  :.:.
Zfish    74 EKWIKMVKKWEKYHNSEKMMKR-VYKGIPLKLRGQAWALLLDVEKVKQANFRKYEKMKE--QAKR 135

  Fly   106 FDKEISDSISIDLPRTFPDNI----HFDMKKQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVT 166
            :..||. .|.:|:.|||.::|    .|.:|:|.|:::|.||:.:|.:|.||||::.||.:||:..
Zfish   136 YSTEIK-QIDLDVNRTFRNHIMFMERFGVKQQALFHVLAAYSVYNTEVSYCQGMSQIAAILLMYM 199

  Fly   167 DDEEKSFWLLKHIVEN--------IVPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLP 223
             :||.:||.|..::.|        .:|.:...:...:..|     :::.:.:..:..|::...:.
Zfish   200 -NEEDAFWALSQLLTNQKHAMHGFFIPGFPKLHRFQVHHD-----KILSKLLSKLRNHLEKEQMS 258

  Fly   224 YPVIASKWFICIFAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAI--LGCDDI----- 281
            ..:..:|||:..|.:..|....||:||....||.|::...|.|:...||..:  |..:|:
Zfish   259 TGIYTTKWFLQCFIDRTPFTLTLRLWDIYILEGEKVLTAMAYTLLKLHKKHLLKLSLEDLREFLQ 323

  Fly   282 ---AALANLFRDTMIQ 294
               |:..|:..|.:|:
Zfish   324 ERTASSFNMSDDVVIE 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	58/225 (26%)
si:dkeyp-19e1.3	XP_005170766.1	TBC	96..301	CDD:214540	55/213 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810