DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and rabgap1l

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001361730.1	Gene:	rabgap1l / 550007	XenbaseID:	XB-GENE-483580	Length:	1056	Species:	Xenopus tropicalis

Alignment Length:	255	Identity:	67/255 - (26%)
Similarity:	120/255 - (47%)	Gaps:	25/255 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 MKWEAILQQNTDLTQVDAKLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDK 108
            :||      :::|:.....|...:::|||...|.:||..::|....|... |.::.|:
Frog   511 VKW------HSNLSVKPKGLSSLVKRGIPEALRAEVWQLLAGCHENQEML-DKYKMLV------- 561

  Fly   109 EISDS-----ISIDLPRTFPDNIHFDMK----KQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLI 164
             :.||     |..|:.||||.:.:|...    ::.||.:...|:.::..:|||||::::|.:||:
Frog   562 -VKDSAQDSVIRRDIHRTFPAHDYFKNTEGDGQESLYKMCKVYSLYDEVIGYCQGMSFLAAVLLL 625

  Fly   165 VTDDEEKSFWLLKHIVENIVPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIAS 229
            ...:|:....|:|.:.:......:.:|..:|.........|:..::|.:..|...|.|...:.||
Frog   626 HMPEEQAFCVLVKIMYDYQFRNLYQNNFEDLHCKFYQLERLLQEQLPDLYSHFVALNLEAHMYAS 690

  Fly   230 KWFICIFAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAILGCDDIAALANLFR 289
            :||:.:|....|:..|..|.|.:.:||..|:|..||.:..|.|..:|..|...|| ..||
Frog   691 QWFLSLFTAKFPLCMVFHIMDLLLSEGLSIIFHVALALLKTSKEDLLQADFEGAL-KFFR 749

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	57/217 (26%)
rabgap1l	NP_001361730.1	PTB_Rab6GAP	123..251	CDD:269922
		DUF3694	284..415	CDD:372133
		TBC	528..737	CDD:214540	57/217 (26%)
		Smc	753..>1011	CDD:224117
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910