DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and tbc1d15

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	XP_005159143.1	Gene:	tbc1d15 / 492676	ZFINID:	ZDB-GENE-041111-251	Length:	665	Species:	Danio rerio

Alignment Length:	241	Identity:	54/241 - (22%)
Similarity:	95/241 - (39%)	Gaps:	61/241 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 KFMDGYLKTLTRRRMKWEAILQQNTDLTQVDAKLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSP 94
            ||:.||        ..|.:..::...|.:  .|...|.|..:.       |..:|  ...:||:.
Zfish   336 KFLLGY--------FPWSSTHEERKLLQK--RKTDEYFRMKLQ-------WKSVS--EEQERRNS 381

  Fly    95 DL--FRNLLRTEPFDKEISDSISIDLPRTFPDNIHFDMKKQ----RLYNILIAYAHHNRDVGYCQ 153
            .|  :|:|             |..|:.||..:|..::....    .|::||:.|..::.|:||.|
Zfish   382 RLRDYRSL-------------IEKDVNRTDRNNKFYEGLDNPGLILLHDILMTYCMYDFDLGYVQ 433

  Fly   154 GLNYIAGLLLIVTDDEEKSFW----LLKHIVENIVPQYHSH-----NMANLLR--DLAVFRELVI 207
            |::.:...:|.|.::|..:||    .:..:.||...|....     .::.|||  |||.:..|
Zfish   434 GMSDLLSPILFVMENEVDAFWCFVSFMDEMHENFEEQMQGMKTQLIQLSTLLRLLDLAFWNYL-- 496

  Fly   208 RRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLRIWDCVF 253
                    ...:.|  |.....:|.:..|...|..:.|||:|:.::
Zfish   497 --------EAQDSG--YLYFCFRWLLIRFKRELHFQDVLRLWEVMW 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	46/204 (23%)
tbc1d15	XP_005159143.1	DUF3548	4..220	CDD:192931
tbc1d15	XP_005159143.1	TBC	322..557	CDD:214540	54/241 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810