DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and CG42795

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001287272.1	Gene:	CG42795 / 41252	FlyBaseID:	FBgn0261928	Length:	3213	Species:	Drosophila melanogaster

Alignment Length:	288	Identity:	83/288 - (28%)
Similarity:	140/288 - (48%)	Gaps:	34/288 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 KLKRYIRKGIPGPYRPDVW-------MKISGAAAAQRRSPDLFRNLLRTEPFDKEISDSISIDLP 119
            ||...:..|.|..:|..:|       :|......||:|. ..|....|.:  |:|:...|..||.
  Fly   213 KLVARLPGGTPPEFRRKLWLSLADKYLKSKNVDWAQQRE-KCFCEEWRED--DEELGIQIVKDLH 274

  Fly   120 RTFPDNI----HFDMKKQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTD-DEEKSFWLLKHI 179
            || ..|:    ...:.:.:|..||:.||.:|.:||||||.|.:..|:|.|.| :||:|..::.::
  Fly   275 RT-GSNLCTGPAGSINQAKLKRILLGYARYNPEVGYCQGFNMLGALILQVMDKEEEESMKVMIYL 338

  Fly   180 VENIVPQ-YHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYP---------VIASKWFIC 234
            ||.::|. |...:|..|..|:.|||||:..|:|.:.:|:..|..|..         |...:||:.
  Fly   339 VEGVLPTGYFYGSMGGLQADMGVFRELMQTRLPRLAKHLQRLQGPVENAFEPPLTNVFTMQWFLT 403

  Fly   235 IFAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAIL---GCDDIAALANLFRDTMIQDN 296
            :|...||:..|||:||.|..||..::.|.||.::...:..::   ..|:.......:...::..:
  Fly   404 MFCTCLPMSCVLRVWDLVLIEGSDVLLRTALVLWSLLEERVISVRSADEFYGKMGSYSSELLNGH 468

  Fly   297 IVTDCHGFVEAMFSLRLKRSELESLRKV 324
            :| |.:|.:|.:    :|...:|.||::
  Fly   469 LV-DSNGLIERV----VKLGPIEDLRQL 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	72/230 (31%)
CG42795	NP_001287272.1	RabGAP-TBC	268..443	CDD:278964	60/175 (34%)
		DUF4682	560..684	CDD:292361
		DBP	1112..1415	CDD:289157
		SWIRM-assoc_2	<2376..2482	CDD:293105
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456598
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.750