DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and Sgsm3

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_942082.2	Gene:	Sgsm3 / 362963	RGDID:	735113	Length:	763	Species:	Rattus norvegicus

Alignment Length:	301	Identity:	84/301 - (27%)
Similarity:	147/301 - (48%)	Gaps:	20/301 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 DEYGFKRGDHFDYNNYSKFMDGYLKTLTRRRMKWEAILQ--QNTDLTQV-----------DAKLK 64
            ||:||:..........|:.....|.....:|::|:|.|:  .|.|:..:           ..||:
  Rat    57 DEFGFRVDKEGSEPGCSQMAGTPLVEDPPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLR 121

  Fly    65 RYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKEI-SDSISIDLPRTFPDNIHF 128
            ..:..|||...||.:||::|||...::.|...:|.:::....|:.| :..|..||.||.|.|..|
  Rat   122 SLVLAGIPHGMRPQLWMRLSGALQKKKNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACF 186

  Fly   129 ----DMKKQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEEKSFWLLKHIVENIVP-QYH 188
                .:...||..:|.|.|....::|||||...:|..||:.. :||.:||::..|:|:::| .|.
  Rat   187 ANVNSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFL-EEEDAFWMMCAIIEDLLPASYF 250

  Fly   189 SHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLRIWDCVF 253
            |..:..:..|..|.|.|:::.:|.:::.:....:...:|...||:..||.|:.:..:|||||..|
  Rat   251 STTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVHIRLLLRIWDLFF 315

  Fly   254 AEGYKIVFRAALTMFVTHKNAILGCDDIAALANLFRDTMIQ 294
            .||..::|:..|.|....:..::..::.|::.|...|...|
  Rat   316 YEGSLVLFQTTLGMLRLKEEELIQSENSASIFNTLSDIPAQ 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	66/214 (31%)
Sgsm3	NP_942082.2	TBC	127..338	CDD:214540	66/211 (31%)
		SH3_SGSM3	497..549	CDD:212747
		RUN	576..727	CDD:397055
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820