DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and Grtp1

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001163948.1	Gene:	Grtp1 / 361180	RGDID:	1309210	Length:	342	Species:	Rattus norvegicus

Alignment Length:	311	Identity:	133/311 - (42%)
Similarity:	198/311 - (63%)	Gaps:	8/311 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ASSKFSDVDEYGFKRGDHFDYNNYSKFMDGYLKTLTRRRMKWEAILQQNTDLTQVDAKLKRYIRK 69
            |.::...:|.|||:|.:.|||..|.:|...||..||:|.:||..:|:.:..:.: ...:|||:||
  Rat    10 ARARVPRIDPYGFERPEDFDYAAYEEFFSTYLVILTKRAIKWSKLLKGSGGVRK-SVTVKRYVRK 73

  Fly    70 GIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKEISDSISIDLPRTFPDNIHF-----D 129
            |||..:|..|||.:|||.|...::|..:..||..|. ...:.::|..||.||||||:.|     .
  Rat    74 GIPLEHRARVWMAVSGAQAQMDQNPGYYHRLLEGES-SSRLEEAIRTDLNRTFPDNVMFRKTADP 137

  Fly   130 MKKQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEEKSFWLLKHIVENIVPQYHSHNMAN 194
            ..::.|||:|:||..||:|||||||:|:|||.|:::|.:||:|||||..:|..|:|.|:|..|..
  Rat   138 CLQKTLYNVLLAYGLHNQDVGYCQGMNFIAGYLILITKNEEESFWLLDALVGRILPDYYSPAMLG 202

  Fly   195 LLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLRIWDCVFAEGYKI 259
            |..|..|..|||..::|||...:|..|:.:.::.|:||||:|.::||||||||||||:|.||.||
  Rat   203 LKTDQEVLAELVRMKLPAVAALMDGHGVLWTLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKI 267

  Fly   260 VFRAALTMFVTHKNAILGCDDIAALANLFRDTMIQDNIVTDCHGFVEAMFS 310
            :||.|||:...|:..||....:..:.:.|:. :.:.:.||:||.|::.:||
  Rat   268 IFRVALTLIKQHQEFILEASSVPDICDKFKQ-ITKGDFVTECHTFMQKIFS 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	101/213 (47%)
Grtp1	NP_001163948.1	TBC	71..284	CDD:214540	101/213 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	177	1.000	Domainoid score	I3507
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H84592
Inparanoid	1	1.050	207	1.000	Inparanoid score	I3637
OMA	1	1.010	-	-		QHG53652
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	1	1.000	-	-		FOG0003486
OrthoInspector	1	1.000	-	-		oto97045
orthoMCL	1	0.900	-	-		OOG6_100958
Panther	1	1.100	-	-	LDO	PTHR22957
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2377
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.980